Our work at the Hauptman-Woodward Institute uses a variety of techniques to study protein structure and function; the main goal of our work is to figure out how enzymes use specific structures to catalyze interesting chemical reactions. We use a variety of techniques, including molecular and structural biology, as well as enzymology and other biophysical tools to understand protein structure and function. We have additionally developed novel chemical inhibitors that can be used to probe protein function in biological systems.
In particular, we are focused on Natural Product Synthesis and the fascinating proteins that bacteria use to make novel chemicals. Our lab is interested in understanding the enzymatic basis for these biosynthetic pathways, as well as the role that novel compounds play in bacterial growth and pathogenesis.
Andrew M. Gulick
Principal Research Scientist, Hauptman-Woodward Medical Research Institute
700 Ellicott St.
Buffalo, NY 14203-1102
My HWI Web Page
HWI is an independent research institute. Admission to our graduate program usually occurs through the PPBS, an interdisciplinary PhD Program in Biological Sciences at UB.