>NC_002645_HCoV-229E_inf-1_nsp3_2984..7744_4761bp_1587aa
--G-KVSFSDDVEVKDIEP--VYR-VKLCFEFEDEKLVDVCEKAI-GKKIKHEGD-WDSF
CKTIQSALSVV---------SCYVNLPTY----------YIYDEEGGNDLSLP--VMISE
WPLSVQQAQ--------------------------------QEATLPDIAE---------
-----------------DVVDQVEEVNSIF------------------------------
--------------DIETVDVKHDVSPFEMPFEELNGLKILKQLDNNCWVNSV-------
----MLQIQLTGILDGDYAMQFFK---MGRVAKMIERCYTAEQCIRGAMGDVGLCMYRL-
---LKDLHTGFMVMDYKCSCTSGRLEESGAVLFCTPTKKA---FPYGTCLNCNAPRMCTI
RQLQGTIIFVQQKPEPVNPVS-FVVKP--------------------VCSSIFRGAVSCG
HYQTNIYSQNLCVDGFGVNKIQPWT----NDALNTICIKDADY--------------NAK
VEISVTPIKNTVDTTPKEEFVVKEKLNAF--LVHDNVAFYQGDVDTVVNGVDFDF----I
VNAANENLAHGGGLAKALDVYTKGKLQRLSKEHIGLAGKVKVGTGVMVE--CDSL---RI
FNVVGP--RKG-KHERDLLIKAYNTINNEQGTP-LTPILSCGIFGIKLETSLEVLLDVCN
TKEVKVFVYTDTEVCKVK------------------------------------------
------------------------------------------------------------
--------------DFVSGLVNVQKVEQPKIEPKPVSVIKVAPKPYRVDGKFSYF-----
------TEDL-----------------------------LCVADDKPIVLFTDSMLTLDD
RGLALDNALSGVLSAAIKDCVDINKA----------------IPSGNLIKFDIG------
----SVVVYMCVVPSEKD-------------------------------KHLDNNVQRCT
RKLNRLMCDIVCTIPADYILPLVLSSLTCN------VSFVGELKAA---EAKVITIKVTE
D------GVNVHDVTVTTDKSFEQQV-GVIADKDKDLSGAVPSDLNTSELLTKAIDVD--
----WVEFYGFKDAVT---FATVDHSAFAYESAVVNGIRVLKTSDNNCWVNAVCIALQYS
K-PHFISQGLDAAWNKFVLGDVEIFVAFVYYVARLMKGDKGDAEDTLTKLSKYLANEAQV
QLEH--YSSCVECDAKFKNSVASINSAIVCAS----VKRDGVQVGY---CVHGIKYYSRV
RSVRGRAIIVSV----EQLEPCAQSRLLSGVAYTAFSGPVDK--GHYTVYDTAKKS--MY
DGDRFVKHDLSLLSVTSVVM----------------------------------------
----------------VGGYVAPVNT----------------------------------
-----VKPKPVINQLDEKAQKF--------------------------------------
------------------------------------------------------------
----------------------------FDFGDFLIHN----------------------
------------------------------------------------------------
-------------------------FVIFFTWLLSMFTLCKTAVTTGDV-----KIMAKA
PQRTGVVLKRSLK------YNLKASAAVLKSKWWLLAKFTKLL-----LLIYTLY-SVVL
LCVRFGPFN--------------------------FCSETVNGYAKSN-FVKDDYCDG-S
LGCKMCLFGYQELSQFSHLDVVWKHITDP------LFSNMQPFIVMVLLLIFGDNYLRCF
LLYFVAQMISTVGVFLGYKETNWFLHF-------IPFDVICDELLVTVIVIKVISFVRHV
LFGCENPDCIACSKSARLKRFPVNTIVNGVQRSFYVNANGGSKFCKKHRFFCVDCDSYGY
GSTFITPEVSRELGNITKTNVQPTGPAYVMIDKVEFENGFYRLY------SCETFWRYNF
DITESKYSCKEVFK--------NCNVLDDFIVFN-NNGTNVTQVKNASVYFSQLLCRPIK
LVDSELLSTL--SVDFNGVLHKAYIDVLRNSFGKDLNANMSL------------------
---AECKR----ALGL-SISDHEFTSAISNAHRCDVLLSDLSFNNFVSSYAKPEEK-LSA
YDLACCMRAGAKVVNANVLTKDQTPIVWHAKDFNSLSAEGRKYIVKTSKAKGLTFLLTIN
ENQAVTQIPATSI--VAKQ-GA
>NC_005831_HCoV-NL63_AmsterdamI_nsp3_2981..7672_4692bp_1564aa
--G-KISFSDDVIVHDVEP--THK-VKLIFEFEDDVVTSLCKKSF-GKSIIYTGD-WEGL
HEVLTSAMNVI---------GQHIKLPQF----------YIYDEEGGYDVSKP--VMISQ
WPISNDSN---------------------------------GCVVEASTDFHQL------
-----------------ECIVDDSVREEVD------------------------------
---------IIEQPFEEVEHVLSIKQPFSFSFRDELGVRVLDQSDNNCWISTT-------
----LVQLQLTKLLDDSIEMQLFK---VGKVDSIVQKCYELSHLISGSLGDSGKLLSEL-
---LKEKYTCSITFEMSCDCGKKFDDQVGCLFWIMPYTKL---FQKGECCICHKMQTYKL
VSMKGTGVFVQDPA-PIDIDA-FPVKP--------------------ICSSVYLGVKGSG
HYQTNLYSFNKAIDGFGVFDIK-------NSSVNTVCFVDVDF-----------------
----------------HSVEIEAGEVKPF--AVYKNVKFYLGDISHLVNCVSFDF----V
VNAANENLLHGGGVARAIDILTEGQLQSLSKDYISSNGPLKVGAGVMLE--CEKF---NV
FNVVGP--RTG-KHEHSLLVEAYNSILFENGIP-LMPLLSCGIFGVRIENSLKALFSCDI
NKPLQVFVYSSNEEQAVL------------------------------------------
------------------------------------------------------------
-------------------------KFLDGLDLTPVIDDVDVVKPFRVEGNFSFF-----
------DCG------------------------------VNALDGDIYLLFTNSILMLDK
QGQLLDTKLNGILQQAALDYLATVKT----------------VPAGNLVKLFVE------
----SCTIYMCVVPSIND-------------------------------LSFDKNLGRCV
RKLNRLKTCVIANVPAIDVLKKLLSSLTLT---VKFVVESNVMDVNDCFKNDNVVLKITE
D------GINVKDVVVESSKSLGKQL-GVVSDGVDSFEGVLP--INTDTVLSVAPEVD--
----WVAFYGFEKAAL---FASLDVKPYGYPNDFVGGFRVLGTTDNNCWVNATCIILQYL
K-PTFKSKGLNVLWNKFVTGDVGPFVSFIYFITMSSKGQKGDAEEALSKLSEYLISDSIV
TLEQ--YSTCDIC----KSTVVEVKSAIVCAS----VLKDGCDVGF---CPHRHKLRSRV
KFVNGRVVITNV----GEPIISQPSKLLNGIAYTTFSGSFDN--GHYVVYDAANNA--VY
DGARLFSSDLSTLAVTAIVV----------------VGGCVTSNVP--------------
-------------------TIVSEKI----------------------------------
---------SVMDKLDTGAQKF--------------------------------------
------------------------------------------------------------
----------------------------FQFGDFVMNN----------------------
------------------------------------------------------------
-------------------------IVLFLTWLLSMFSLLRTSIMKHDI-----KVIAKA
PKRTGVILTRSFK------YNIRSALFVIKQKWCVIVTLFKFL-----LLLYAIY-ALVF
MIVQFSPFNSL------------------------LCGDIVSGYEKST-FNKDIYCGN-S
MVCKMCLFSYQEFNDLDHTSLVWKHIRDP------ILISLQPFVILVILLIFGNMYLRFG
LLYFVAQFISTFGSFLGFHQKQWFLHF-------VPFDVLCNEFLATFIVCKIVLFVRHI
IVGCNNADCVACSKSARLKRVPLQTIINGMHKSFYVNANGGTCFCNKHNFFCVNCDSFGP
GNTFINGDIARELGNVVKTAVQPTAPAYVIIDKVDFVNGFYRLY------SGDTFWRYDF
DITESKYSCKEVLK--------NCNVLENFIVYN-NSGSNITQIKNACVYFSQLLCEPIK
LVNSELLSTL--SVDFNGVLHKAYVDVLCNSFFKELTANMSM------------------
---AECKA----TLGL-TVSDDDFVSAVANAHRYDVLLSDLSFNNFFISYAKPEDK-LSV
YDIACCMRAGSKVVNHNVLIKESIPIVWGVKDFNTLSQEGKKYLVKTTKAKGLTFLLTFN
DNQAITQVPATSI--VAKQ-GA
>NC_002306_TGEV_PUR46-MAD_nsp3_2952..7478_4527bp_1509aa
-GDKTVSFSEEVDVQEIAP--VTR-VKLEFEFDNEIVTGVLERAI-GTRYKFTGTTWEEF
EESISEELDAIFDTL----ANQGVELEGY----------FIYDTCGGFDIKNPDGIMISQ
YDINITADEKSEVSAS-------SEEEEVESVE--------EDPENEIVEASEGAEGTSS
QEEVETV----------EVADITSTEEDVD--IVEVSAK---------------------
-------DDPWAAAVDVQEAEQFNPSLPPFKTTNLNGKIILKQGDNNCWINAC-------
----CYQLQAFDFFNNE-AWEKFK---KGDVMDFVNLCYAATTLARGHSGDAEYLLELM-
---LNDYSTAKIVLAAKCGCGEKEIVLERAVFKLTPLKES---FNYGVCGDCMQVNTCRF
LSVEGSGVFVHDILSKQTPEAMFVVKP--------------------VMHAVYTGTTQNG
HYMVDDIEHGYCVDGMGIKPLK-------KRCYTSTLFINANVMTRAEKPKQEFKVEKVE
QQPIVEENKSSIEKEEIQSPKNDDLILPF--YKAGKLSFYQGALDVLINFLEPDV----I
VNAANGDLKHMGGVARAIDVFTGGKLTERSKDYLKKNKSIAPGNAVFFENVIEHL---SV
LNAVGP--RNGDSRVEAKLCNVYKAIAKCEGKI-LTPLISVGIFNVRLETSLQCLLKTVN
DRGLNVFVYTDQERQTIE------------------------------------------
------------------------------------------------------------
----------------------------------------------------NFF-----
------SC----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------SIPVNVTE
D------NVNHERVSVSFDKTYGEQLKGTVVIKDKDVTNQLPSAFDVGQKVIKAIDID--
----WQAHYGFRDAAA---FSASSHDAYKFEVVTHSNFIVHKQTDNNCWINAICLALQRL
K-PQWKFPGVRGLWNEFLERKTQGFVHMLYHISGVKKGEPGDAELMLHKLGDLMDNDCEI
IVTH--TTACDKC-----AKVEKFVGPVVAAP----LAIHGTDET----CVHGVSVNVKV
TQIKGTVAITSL----IGPIIGEV---LEATGYICYSGSNRN--GHYTYYDNRNGL--VV
DAEKAYHFNRDLLQVTTAIA-----------------------------SNFVVKKPQA-
EERPKNCAF--NKVAASPKIVQEQKL----------------------------------
-LAIESGANYALTEFGRYADMF--------------------------------------
------------------------------------------------------------
----------------------------FMAGDKILRL----------------------
------------------------------------------------------------
-------------------------LLEVFKYLLVLF-MCLRSTKMPKV-----KVKPP-
------LAFKDFG------AKVRTLNYMRQLNKPSVWRYAKLV-----LLLIAIY-NFFY
LFVSIPVVHKL------------------------TCNGAVQAYKNSS-FIKSAVCGN-S
ILCKACLASYDELADFQHLQVTWDFKSDP------LWNRLVQLSYFAFLAVFGNNYVRCF
LMYFVSQYLNLWLSYFGYVEYSWFLHV-------VNFESISAEFVIVVIVVKAVLALKHI
VFACSNPSCKTCSRTARQTRIPIQVVVNGSMKTVYVHANGTGKFCKKHNFYCKNCDSYGF
ENTFICDEIVRDLSNSVKQTVYATDRSHQEVTKVECSDGFYRFY------VGDEFTSYDY
DVKHKKYSSQEVLK--------SMLLLDDFIVYS-PSGSALANVRNACVYFSQLIGKPIK
IVNSDLLEDL--SVDFKGALFNAKKNVIKNSFNVDVSECKNL------------------
---DECYR----ACNL-NVSFSTFEMAVNNAHRFGILITDRSFNNFWPSKVKPGSSGVSA
MDIGKCMTSDAKIVNAKVLTQRGKSVVWLSQDFAALSSTAQKVLVKTFVEEGVNFSLTFN
AVGSDDDLPYERFTESVSPKSG
>NC_003436_PEDV_CV777_nsp3_2982..7847_4866bp_1622aa
--G-DVKFSDEVSVKTIDP--VYK-VSLEFEFESETIMAVLNKAV-GNRIKVTGG-WDDV
VEYINVAIEVL---------KDHVEVPKY----------YIYDEEGGTDPNLP--VMVSQ
WP--LNDDTISQDLLDVEVVTDAPIDSEGDEVD--------SSAPEKVADVANSEPGDDG
L----------------PVAPETNVESEVE------------------------------
-------EVAATLSFIKDTPSTVTKDPFAFDFVSYGGLKVLRQSHNNCWVTST-------
----LVQLQLLGIVDDP-AMELFS---AGRVGPMVRKCYESQKAILGSLGDVSACLESL-
---TKDLHTLKITCSVVCGCGTGERIYEGCAFRMTPTLEP---FPYGACAQCAQVLMHTF
KSIVGTGIFCRDT--TALSLDSLVVKP--------------------LCAAAFIG-KDSG
HYVTNFYDAAMAIDGYGRHQIK-------YDTLNTICVKDVNW-----------------
----------TAPLVPAVDSVVEPVVKPF--YSYKNVDFYQGDFSDLVK-LPCDF----V
VNAANEKLSHGGGIAKAIDVYTKGMLQKCSNDYIKAHGPIKVGRGVMLE--ALGL---KV
FNVVGP--RKG-KHAPELLVKAYKSVFANSGVA-LTPLISVGIFSVPLEESLSAFLACVG
DRHCKCFCYGDKEREAII------------------------------------------
------------------------------------------------------------
KYMDGLVDAIFKEALVDTTPVQEDVQQVSQKPVLP------NFEPFRIEGAHAFY-----
------ECNPEG---------------------------LMSLGADKLVLFTNSNLDFCS
VGKCLNDVTSGALLEAINVFKKSNKT----------------VPAGNCVTLDCA------
---NMISITMVVLPFDGD-------------------------------ANYDKNYARAV
VKVSKLKGKLVLAVDDATL-YSKLSHLSVLGFVSTPDDVERFYANK------SVVIKVTE
D------TRSVKAVKVESTATYGQQI-GPCLVNDTVVTDNKP--VVADVVAKVVPNAN--
----WDSHYGFDKAGE---FHMLDHTGFTFPSEVVNGRRVIKTTDNNCWVNVTCLQLQFA
R-FRFKSAGLQAMWESYCTGDVAMFVHWLYWLTGVDKGQPSDSENALNMLSKYIVPAGSV
TIER---VTHDGC----CCSKRVVTAPVVNAS----VLKLGVEDGL---CPHGLNYIGKV
VVVKGTTIVVNV----GKPVVAPSHLFLKGVSYTTFLDNGNGVVGHYTVFDHGTGM--VH
DGDAFVPGDLNVSPVTNVVV---------------------------------SEQTAVV
IKDPVKKAE---------------------------------------------------
-----LDATKLLDTMNYASERF--------------------------------------
------------------------------------------------------------
----------------------------FSFGDFMSRN----------------------
------------------------------------------------------------
-------------------------LITVFLYILSILGLCFRAFRKRDV-----KVLAGV
PQRTGIILRKSMR------YNAKALGVFFKLKLYWFKVLGKFS-----LGIYALY-ALLF
MTIRFTPIGSP------------------------VCDDVVAGYANSS-FDKNEYC-N-S
VICKVCLYGYQELSDFSHTQVVWQHLRDP------LIGNVMPFFYLAFLAIFGGVYVKAI
TLYFIFQYLNSLGVFLGLQQSIWFLQL-------VPFDVFGDEIVVFFIVTRVLMFIKHV
CLGCDKASCVACSKSARLKRVPVQTIFQGTSKSFYVHANGGSKFCKKHNFFCLNCDSYGP
GCTFINDVIATEVGNVVKLNVQPTGPATILIDKVEFSNGFYYLY------SGDTFWKYNF
DITDSKYTCKEALK--------NCSIITDFIVFN-NNGSNVNQVKNACVYFSQMLCKPVK
LVDSALLASL--SVDFGASLHSAFVSVLSNSFGKDLSSCNDM------------------
---QDCKS----TLGFDDVPLDTFNAAVAEAHRYDVLLTDMSFNNFTTSYAKPEEK-FPV
HDIATCMRVGAKIVNHNVLVKDSIPVVWLVRDFIALSEETRKYIIRTTKVKGITFMLTFN
DCRMHTTIPTVCI--ANKK-GA
>DQ811787_PRCV_ISU-1_nsp3_2941..7458_4518bp_1506aa
-GDKVVSFSDEVDVQEIAP--VTR-VKLEFEFDNEIVTGVLERAI-GTRYTFTGTTWEEF
EESISEELDAIFDTL----ANQGVELEGY----------FIYDTCGGFDIKNPDGIMISQ
YDITADEKSEVSASSEKEEVDSV------------------EENPGVEVEASEGAEGISS
QEEAETV----------EVADLTSTEEDVDIIEV--SAK---------------------
-------DDPWAAAVDVQEAEQFNPSLPPFKTTNLNGKIILKQGDNNCWINAC-------
----CYQLQAFDFFNNE-AWEKFK---KGDVMDFVNLCYAATTLARGHSGDADYLLELM-
---LNDYSTAKIVLAATCGCGEKEIVLERAVFKLTPLKES---FSYGVCGDCMQVNTCRF
LSVEGSGVFVHDILSKQTPESMFIVKP--------------------VMHAVYTGTTQNG
HYMVDDIEHGYCVDGMGIKPLK-------KRCYTSTLFINANVMTRAEKPKQEFKVGKVE
QQLIVEDSKSSIEKEEIQSPKNDDLILPF--YKVGKLSFYHGALDVLINFLEPDV----I
VNAANGDLKHMGGVARAIDVVTGGKLTERSKDYLKKNKSIAPGNAVFFENVIEHL---SV
LNAVGP--RNGDSRVEAKLCNVYKAIAKCEGKI-LTPLISVGIFNVRLETSLQCLLKTVN
DRGLNVFVYTDQERQTIE------------------------------------------
------------------------------------------------------------
----------------------------------------------------NFF-----
------SC----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------SIPVNVTE
D------NVNHERVSVSFDKTYGEQLKGTVVIKDKDVTNQLPSAFDVGQKVVKVIDID--
----WQAHYGFRDAAA---FSASSHDAYKFEVVTHSNFIVHKQTDNNCWINAICLALQRL
K-PQWKFPGVRGLWNEFLERKTQGFVHMLYHISGVKKGEPGDAELMLHKLGDLMDNDCEI
IVTH--TTACDKC-----AKVEKFVGPVVAAP----LAIHGTDET----CVHGVSVNVKV
TQIKGTVAITSL----IGPIIGEV---LEATGYICYSGSNRN--GHYTYYDNRNGL--VV
DAEKAYHFNRDLLQVTTAIA-----------------------------SNFVVKKPQA-
DERPKNCAF--NKAVASPKIVQEQKL----------------------------------
-LAIESGANYALTEFGKYADMF--------------------------------------
------------------------------------------------------------
----------------------------FTAGDKILRL----------------------
------------------------------------------------------------
-------------------------LFAVFKYLLVLG-MCLRSTRMPKV-----KVKPP-
------FSFKDFG------AKVRTLNYMRQLNKPSVWRYAKLV-----LLLIAIY-NFFY
LFVSIPVVHKL------------------------TCNGAVQAYKNSS-FIKSAVCGN-S
ILCKACLASYDELADFQHLQVAWDFKSDP------LWNRLVQLSYFAFLAVFGNNYVRCF
LMYFVSQYLNLWLSYFGYVEYSWFLHV-------VNFESISAEFVIIVIVVKAVLALKHI
VFSCSNPSCKTCSRTARQTRIPIQVVVNGSMKTVYVHANGTGKFCKKHNFYCKNCESYGF
ENTFICDEIVRDLSNSVKQTVYATDRSHQEVTKVECSDGFYRFY------VGDEFTSYDY
DVKHKKYSSQEVLK--------NMLLLDDFIVYS-PSGSALANVRNACVYFSQLIGKPIK
IVNSDLFEDL--SVDFKGALFNAKKNVIKNSFNVDVSECKNL------------------
---EECYK----ACNL-NVSFSTFEMAVNNAHRFGILITDRSFNNFWPSKVKPGSSGVSA
MDIGKCMTSDAKIVNAKVLTQRGKSVVWLSQDFAALSSTAQKVLVKTFVEEGVNFSLTFN
AVGSDDDLPYERFTESVSPKSG
>AY994055_FIPV_79-1146_nsp3_2948..7549_4602bp_1534aa
-GDKSVSFSDNVNVREIEP--VTR-VRLEFEFDNEVVTQVLEKVI-GTKYKFIGTTWEEF
EDSISEKLDKIFDTL----AEQGVELEGY----------FIYDTCGGFDINNPDGVMISQ
YDLNTAADDKSDSDASVEDISLISDNEDVEQIEEDNTST--DDAEDVSSVEGETVSVVDV
EDFVEQVSLVEENNVLTPAVNPDEQLSSVEKKDE-VSAK---------------------
-------NDPWAAAVDEQEAEQPKPSLTPFKTTNLNGKIILKQQDNNCWINAC-------
----CYQLQAFDFFNHD-LWDGFK---KDDVMPFVDFCYAALTLKQGDSGDAEYLLETM-
---LNDYSTAKVTLSAKCGCGVKEIVLERTVFKLTPLRNE---FKYGVCGDCKQINMCKF
ASVEGSGVFVHDRIEKQTPVSQFIVTP--------------------TMHAVYTGTTQSG
HYMIEDCIHDYCVDGMGIKPRK-------HKFYTSTLFLNANV-------------MTAK
SKTMVEPPVPVEDKCVEDCQSPKDLILPF--YKAGKVSFYQGDLDVLINFLEPDV----L
VNAANGDLRHVGGVARAIDVFTGGKLTKRSKEYLKSSKAIAPGNAVLFENVLEHL---SV
LNAVGP--RNGDSRVEGKLCNVYKAIAKCDGKI-LTPLISVGIFKVKLEVSLQCLLKTVT
DRDLNVFVYTDQERVTIE------------------------------------------
------------------------------------------------------------
----------------------------------------------------NFF-----
------NG----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------TIPIKVTE
D------TVNQKRVSVALDKTYGEQLKGTVVIKDKDVTNQLPSVSDVGEKVVKALDVD--
----WNAYYGFPNAAA---FSASSHDAYEFDVVTHNNFIVHKQTDNNCWVNAICLALQRL
K-PTWKFPGVKSLWDAFLTRKTAGFVHMLYHISGLTKGQPGDAELTLHKLVDLMSSDSAV
TVTH--TTACDKC-----AKVETFTGPVVAAP----LLVCGTDEI----CVHGVHVNVKV
TSIRGTVAITSL----IGPVVGDV---IDATGYICYTGLNSR--GHYTYYDNRNGL--MV
DADKAYHFEKNLLQVTTAIA-------------SNFVANTPKKEIMPKTQAKESKAKESN
TARVFSEVE-----ENPKNIVRKEKL----------------------------------
-LAIESGVDYTITTLGKYADVF--------------------------------------
------------------------------------------------------------
----------------------------FMAGDKILRF----------------------
------------------------------------------------------------
-------------------------LLEVFKYLLVVF-MCLRKSKMPKV-----KVKPP-
------HVFRNLG------AKVRTLNYVRQLNKPALWRYIKLV-----LLLIALY-HFFY
LFVSIPVVHKL------------------------ACSGSVQAYSNSS-FVKSEVCGN-S
ILCKACLASYDELADFDHLQVSWDYKSDP------LWNRVIQLSYFIFLAVFGNNYVRCL
LMYFVSQYLNLWLSYFGYVKYSWFLHV-------VNFESISVEFVIIVVVFKAVLALKHI
FLPCNNPSCKTCSKIARQTRIPIQVVVNGSMKTVYVHANGTGKLCKKHNFYCKNCDSYGF
DHTFICDEIVRDLSNSIKQTVYATDRSYQEVTKVECTDGFYRFY------VGEEFTAYDY
DVKHKKYSSQEVLK--------TMFLLDDFIVYN-PSGSSLASVRNVCVYFSQLIGRPIK
IVNSELLEDL--SVDFKGALFNAKKNVIKNSFNVDVSECKNL------------------
---EECYK----LCNL-DVTFSTFEMAINNAHRFGILITDRSFNNFWPSKIKPGSSGVSA
MDIGKCMTFDAKIVNAKVLTQRGKSVVWLSQDFSTLSSTAQKVLVKTFVEEGVNFSLTFN
AVGSDEDLPYERFTESVSAKSG
>NC_009657_BtCoV-G1_BtCoV/512/2005_nsp3_2985..7886_4902bp_1634aa
--G-VVTISDEVQVRTIDP--VYK-VRLEYEFEDETLVKVCEKAI-GTKLKVTGD-WSNL
LETLEKAMDVV---------RQHLDVPDY----------FVYDEEGGTDLNLT--IMVSQ
WPLSSDSED------DFKAVDDEPNANTDETVDTFAEDVAETQNVQQDVTQDEVEAVCDL
VVKATEE----------GPIEHEELSEDQK------------------------------
-------EVQQALAFIEDKPVVVKPDVFAFSYASYGGLKVLNQSSNNCWVSSA-------
----LVQLQLTGLLDSD-EMQLFN---AGRVSPMVKRCYESQRAIFGSLGDVSACLESL-
---LKDRDGMSITCTIDCGCGPGVRVYENAIFRFTPLKTA---FPMGRCLICSKTLMHTI
TQMKGTGIFCRDA--TALDVDTLVVKP--------------------LCAAVYVGAQDGG
HYLTNMYDANMAVDGHGRHPIK-------FNTINTLCYKDVDW-----------------
-----------------EVSNGSCDVKPF--LTYKNIEFYQGELSALLS-VNHDF----V
VNAANEQLSHGGGIAKALDDLTKGELQVLSNQYVSRNGSIKVGSGVLIK--CKEH---SI
LNVVGP--RKG-KHAAELLTKAYTFVFKQKGVP-LMPLLSVGIFKVPITESLAAFLACVG
DRVCKCFCYTDKERLAIQ------------------------------------------
------------------------------------------------------------
----NFVTSFQTEQPVEPLPVIQEVKGVQLEKPVPDVKVENPCEPFRIEGDAKFY-----
------DLTPSM---------------------------VQSLQVTRLVSFTNSDLCLGS
FVRDCDGYVQGSLGGAIANYKKSNPV----------------LPAGNCVTLKCD------
---GFISFTFVILPKEGD-------------------------------TNYEKNFNRAI
AKFLKLKGSLLVVVEDSSV-FNKISHASVAGYVAKPALVDTLFEAK------PVQVVVTQ
D------QRSFHTVELSTSQTYGQQL-GDCVVEDKKVTNLKP--VSKDKVVSVVPNVD--
----WDKHYGFVDAGI---FHTLDHTMFVFDNNVVNGKRVLRTSDNNCWINAVCLQLQFA
N-AKFKPKGLQQLWESYCTGDVAMFVHWLYWITGVEKGEPSDAENTLNIISRFLKPQGSV
EMLRATSTTCDGT----CSTKRVVSTPVVNAS----VLKVGLDDGN---CVHGLPLVDRV
VSVNGTVIITNVGDTPGKPVVATENLLLDGVSYTVFQDSTTG-VGHYTVFDKEAKL--MF
DGDVLKPCDLNVSPVTSVVV---------------------------------CNNKKIV
VQDPVKRVE---------------------------------------------------
-----LDASKFLDTMNVASEKF--------------------------------------
------------------------------------------------------------
----------------------------FTFGDFVSRN----------------------
------------------------------------------------------------
-------------------------IIVLIVYLFSLLAICFRALKKRDM-----KVMAGV
PERTGIILKRSVK------YNYKALKFFFRLKFQYIKVFLKFS-----LVLYTLY-ALMF
MFIRFTPVGTP------------------------ICKRYTDGYANST-FDKNDYC-G-N
VLCKICLYGYEELSDFTHTRVIWQHLKDP------LIGNILPLFYLVFLIIFGGFFVRIG
ITYFIMQYINAAGVALGYQDNVWLLHL-------LPFNSMGNIIVVAFIVTRILLFLKHV
LFGCDKPSCIACSKSAKLTRVPLQTILQGVTKSFYVNANGGKKFCKKHNFFCVDCDSYGY
GCTFINDVIAPELSNVTKLNVIPTGPATIIIDKVEFSNGFYYLY------SGSTFWKYNF
DITEAKYACKDVLK--------NCNILTDFVVFN-NSGSNVTQVKNACVYFSQLLCKPIK
LVDSALLASL--NVDFSANLHKAFVEVLSNSFGKDLSNCSNM------------------
---NECRE----SLGLSDVPEEEFSAAVSEAHRYDVLISDVSFNNLIVSYAKPEEK-LAV
HDIANCMRVGAKVVNHNVLTKDNVPVVWLAKDFIALSEEARKYIVRTTKTKGINFMLTFN
DRRMHLTIPTISV--ANKK-GA
>EF203064_Bat-CoV-HKU2_HKU2/GD/430/2006_nsp3_2985..7685_4701bp_1567aa
--GKNVAFDDNVTVTEIDP--IFK-VKLSFEFEDEKLIELCKKVI-GSKVKCSS--WSQL
VEIIDTALTAT---------KSYYNVPEY----------FIYDEEGGNDLNLD--VMISE
WPLQVDEVS--------------------------------ELVSTDETVEEQAVEQVE-
-----------------PVVEDVSDIIEVN------------------------------
------------KAFAIDDSPKRAISPFGFDTNEINGRRVLYQSNNNCWVNAA-------
----CYQLQVLGF--DSPAMELYR---VGGTHNLVKQCYEATGAFLGSLGDVAHCLEVL-
---LKDAKTAKVTVEVTCDCSSNFEELSGAFFRFLPLRSK---FEYGSCFACHGTRYYRV
CGIVGSAIFSQTL--KPLDFNDLICDV--------------------ASASVFLG-DDCG
HYLINDYDKRLCVDGMGVYKIR-------HNTIDTIVVKDADI-----------------
---------------------KPSTVAPF--TEYCNVKFYQGDFKDLAG-LSHDF----V
VNAANCNLAHGGGVAKAIDHHTGGKLQKLSTSFVKKNGKVATGECVMID--TGKL---KV
LNAVGP--RKG-KDAESLLNTVYTNIFARKGVP-LMPLISCGIFGFDLKDSLRAFLAACG
DRHVKCFVYSDSERESVM------------------------------------------
------------------------------------------------------------
--------------KFLMTPFEENAATKEVLETPVVEITTDVVAPFYTIGSHKFY-----
------DCNSVEP--------------------------ILGLGVKNIVLFTDQVLSVKD
FGVVVDKHLNGLLSDMSNKYVGDHKA----------------VPFGNILSLDCG------
-----AFTVVDAVSPFDG-------------------------------ASFEKQSGRTI
RKLARLDGSTLCVLPNASALFDKLFALGDNFSFLVLDNVRPLFDNY--LKPKDVKVKVTA
D------GRNVNDVVVTTAETFDAQL-GPSANGVESLVGVVPTPMDSGRVVNTAPDVN--
----WSKHFGFSDAAA---FAVLDHSKFAFDSEVVDGKRALADSDNNCWVNATCLALQFL
K-PTFKYVGWEDLWNKLRSGDVAGFVHLLYYIEGVDKGAKGDVESTLSKLDKYIVSSGSV
TVER--STLCDRC----NSTVKTVTGAIAEAS----VILNGHADGH---CPHNFEWRVQV
VGVKGDIILLHSGSLLNGPYVY-------GDAYVAFSGNIDN--GHYTVFDNKLSK--MY
DGIKCVKTTLDTLVASSVVI----------------------------------RNGSYA
VK----------------------------------------------------------
-----TEHVPLIKKLDDSAEKF--------------------------------------
------------------------------------------------------------
----------------------------FNVGDIVAHN----------------------
------------------------------------------------------------
-------------------------IAYFFVWLLTTLSTLYRCWRGGNF-----KLLSSI
PERSGIVLRRSFK------YNFRALRSNVASKQKYCLMFAKLL-----LLLYTIY-AMLF
ILVRFSFFNDY------------------------ICGSAVRGYASSD-FDKSKFCNG-S
LVCKTCLFGYQELSEFQHVGVVWSYVREP------LFASVLPLCYFAVIAIFGGVVERFA
LCYFAAQFINNVLSFLKLQDSFWLVQL-------VPFDIFGDEILVMFLSYKAICFFKHV
VFGCDKPSCVACCKSAKLKRIAMDTIVNGSRRSFYVNANGGAKLCKKHNFFCVACDSYGS
GHTYINDHIANELHNVTKLHVKPTGPAFINVDRVEFSDGFYRIF------SGDKFWKYNF
DITDKKFSCKEVLK--------NCNILDDFIVFD-NNGSNLSQVQNACVYLSQLLCKPIK
IIDSTLLSSL--NVDFNGALHKAFLDVLHNSFGKDFSSCKTM------------------
---HDCKE----LLEL-DVSDDDFIKVVSDAHRFDVLITDTSFNNFCTSYAKPAEK-LSS
FDLAHCMRSGAKVVNHNVLIKEKMPIVWNCVDFAKLSVDARKYIVKTAKVKGVTFLLTVN
NNVMETTLPCVSV--LQKQ-GA
>NC_005147_HCoV-OC43_OC43_nsp3_2764..8460_5697bp_1899aa
--GRRVTFKEQPTVKEIIS--MPKIIKVFYELDNDFNTIL-NTAC-GVFEVDDTVDMEEF
YAVVIDAIEEKLSPC-KELEGVGAKVSAF-LQKLEDNPLFLFDEAGEEVLAPK--LYCAF
TAPEDDDFLEE------------------------------SDVEEDDVEGEETDLTVTS
AGQ--------------PCVASEQEESSEV------------------------------
----------------------------LEDTLDDGPSVETSDSQVEEDVEMS-------
-----------------------------DFVDLESVIQDYENVCFEFYTTEPEFVKVLG
LYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYK---QQYSQLFVDTLVNKIPA
NIVLPQGGYVADFAYWFLTLCDWQCVAYWKCIKCDLALKLKGLDAMFFYGDVVSHICKCG
ESMVLIDVDVPFTAHFALKDKLFCAFITKRIVYKAACVVDVNDSHSMAVVDGKQIDDHRI
TSITSDKFDFIIGHGMSFSMTTFEIAQLYGSCITPNVCFVKGDIIKVSKLVKAEV----V
VNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKSKGVCATGDCYVST--GGKLCK-TV
LNVVGPDARTQGKQSYVLLERVYKHLNNYDCV--VTTLISAGIFSVPSDVSLTYLLGTA-
KKQVVLVSNNQEDFDLIS------------------------------------------
------------------------------------------------------------
-----------------------------------------KCQITAVEGTKKLA-----
------AR-------------------------------LSFNVGRSIVYETDANKLILI
NDVAF---------VSTFNVLQDVLS----------------LRHDIALDDDAR------
---TFVQSNVDVVP-----------------------------EGWRVVNKFYQINGVRT
VKYFECTGGIDICSQDKVFGYVQQGIFNKA----TVAQIKALFLDK-------VDILLTV
D------GVNFTNRFVPVGESFGKSL-GNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE
DLKAVRSSFNFDQKELLA-YYNMLVNCFKWQVVVNGKYFTFKQANNNCFVNVSCLMLQSL
H-LTFKIVQWQEAWLEFRSGRPARFVALVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAI
CDFE---IACK-C----GVKQEQRTGLDAVMH-FGTLSREDLEIGYTVDCSCGKKLI-HC
VRFDVPFLICS-----NTPASVKL--PKGVGSANIFIGDKV---GHYVHVKCEQSY-QLY
DASNVKKVTDVTGKLSDCLYLKNLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYY
TQRIIKAQF--KTFEKVDGVYTNFKLIGHT-------VCDSLNAKLGFDSSKEFV-EYKI
TEWPTATGDVVLATDDLYVKRYERGCITFGKPVIWLSHEKA----------SLNSLTYFN
RPSLVDDNKFDVLKVDD-----------------------------------------VD
DGGDSSESGAKETK-EINIIKLSGVKKPFKVEDSVIVNDDTSETKYVKSLSIVDVYDMWL
T-GCKYVVRTANALSRAVNVPT--------------IRKFIKFGMT---------LVSIP
IDLLNLREIKPAVNVVKAVRNKISVCFNFIKWLFVLLFGWIKISADNKV-----------
-----IYTTEIASKLTCKLVALAFKNAFLTFKWSMVARGACII-----ATIFLLWFNFIY
ANVIFSDFYLPKIGFLPTFVGKIAQWIKNTFSLVTICDLYSMQDVGFK----NQYCNG-S
IACQFCLAGFDMLDNYKAIDVV-QYEADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLF
ALISIQILTTWLPELFMLSTLHWSFRLLVALANMLPAHVFMRFYIIIASFIKLFSLFRHV
AYGCSKSGCLFCYKRNRSLRVKCSTIVGGMIRYYDVMANGGTGFCSKHQWNCIDCDSYKP
GNTFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQVGCSMRLFY-----DRDGQRTYD-
DVNASLFVDYSNLL----HSKVKSVPNMHVVVVE--NDADKANFLNAAVFYAQSLFRPIL
MVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIATAHSSIKQGTQIYKVL
DTFLSCARKSC-SIDS-DVDTKCLADSVMSAVSAGLELTDESCNNLVPTYLKSDN--IVA
ADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQFSSDFQHKLKKACCKTGLKLKLTYN
KQMANVSVLTTPF--SLK--GG
>NC_006577_CoV-HKU1A_N1_nsp3_2633..8719_6087bp_2029aa
--GRKVNFNEKPVVMEIPS--LMT-VKVMFDLDSTFDDIL-GKVC-SEFEVEKGVTVDDF
VAVVCDAIENALNSC-KEHPVVGYQVRAF-LNKLNENVVYLFDEAGDEAMASR--MYCTF
AI--EDVEDVISSEAVEDTIDGVVEDTINDDEDVVTGDNDDEDVVTGDNDDEDVVTGDND
DEDVVTGDNDDE-----DVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDVV
TGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNNDEEIV
TGDNDDQIVVTGDDVDD-IESIYDFDTYKALLVFNDVYNDALFVSYGSSVETETYFKVNG
LWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYK---VGYNQSFVDYLLTTIPK
AIVLPQGGFVADFAYWFLNQFDINAYANWCCLKCGFSFDLNGLDALFFYGDIVSHVCKCG
HNMTLIAADLPCTLHFSLFDDNFCAFCTPKKIFIAACAVDVNVCHSVAVIGDEQIDGKFV
TKFSGDKFDFIVGYGMSFSMSSFELPQLYGLCITPNVCFVKGDIINVARLVKADV----I
VNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMVKSKGVCQVGDCYVST--GGKLCK-TI
LNIVGPDARQDGRQSYVLLARAYKHLNNYDCC--LSTLISAGIFSVPADVSLTYLLGVV-
DKQVILVSNNKEDFDIIQ------------------------------------------
------------------------------------------------------------
-----------------------------------------KCQITSVVGTKALA-----
------VR-------------------------------LTANVGRVIKFETDAYKLFLS
GDDCF---------VSNSSVIQEVLL----------------LRHDIQLNNDVR------
---DYLLSKMTSLP-----------------------------KDWRLINKFDVINGVKT
VKYFECPNSIYICSQGKDFGYVCDGSFYKA----TVNQVCVLLAKK-------IDVLLTV
D------GVNFKSISLTVGEVFGKIL-GNVFCDGIDVTKLKCSDFYADKILYQYENLSLA
DISAVQSSFGFDQQQLLA-YYNFLTVCK-WSVVVNGPFFSFEQSHNNCYVNVACLMLQHI
N-LKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGAI
CELE---LICD-C----GIKQESRVGVDAVMH-FGTLAKTDLFNGYKIGCNCAGRIV-HC
TKLNVPFLICS-----NTPLSKDL--PDDVVAANMFMGVGV---GHYTHLKCGSPY-QHY
DACSVKKYTGVSGCLTDCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYY
TKPIIKAQF--KPFAKVDGVYTNFKLVGHD-------ICAQLNDKLGFNVDLPFV-EYKV
TVWPVATGDVVLASDDLYVKRYFKGCETFGKPVIWFCHDEA----------SLNSLTYFN
KPSFKSENRYSVLSVDSVS---------------------------------------EE
SQGNVVTSVMESQI-STKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDMYL
T-GCDYVVWVANELSRLVKSPT--------------VREYIRYGIK---------PITIP
IDLLCLRDDNQTLLVPKIFKARAIEFYGFLKWLFIYVFSLLHFTNDKTI-----------
-----FYTTEIASKFTFNLFCLALKNAFQTFRWSIFIKGFLVV-----ATVFLFWFNFLY
INVIFSDFYLPNISVFPIFVGRIVMWIKATFGLVTICDFYSKLGVGFT----SHFCNG-S
FICELCHSGFDMLDTYAAIDFV-QYEVDRRVLFDYVSLVKLIVELVIGYSLYTVWFYPLF
CLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANMLPAFVLLRFYIVVTAMYKVVGFIRHI
VYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYYDITANGGTGFCVKHQWNCFNCHSFKP
GNTFITVEAAIELSKELKRPVNPTDASHYVVTDIKQVGCMMRLFY-----DRDGQRVYD-
DVDASLFVDINNLL----HSKVKVVPNLYVVVVE--SDADRANFLNAVVFYAQSLYRPIL
LVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNFVNIAHASLREGVQLEKVL
DTFVGCVRKCC-SIDS-DVETRFITKSMISAVAAGLEFTDENYNNLVPTYLKSDN--IVA
ADLGVLIQNGAKHVQGNVAKAANISCIWFIDAFNQLTADLQHKLKKACVKTGLKLKLTFN
KQEASVPILTTPF--SLK--GG
>AY884001_CoV-HKU1B_N2_nsp3_2627..8623_5997bp_1999aa
--GRKVNFNEKPVVMEIPS--LMT-VKVMFDLDSTFDDIL-GKVC-SEFEVEKGVTVDDF
VAVVCDAIENALNSC-KDHPVVGYQVRAF-LNKLNENVVYLFDEAGDEAMASR--MYCTF
AI--EDVEDVISSEAVEDTIDGVVEDTINDDEDVVTGDNDDEDVVTGDNDDEDVVTGDND
DEDVVTGDNDDE-----DVVTGDNDDEDVVTGDND--DE---------------------
-------DVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEEIV
TGDNDDQIVVTGDDVDD-IESVYDFDTYKALLVFNDVYNDALFVSYGSSVETETYFKVNG
LWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYK---VGYNQSFVDYLLTTIPK
AIVLPQGGYVADFAYWFLNQFDINAYANWCCLKCGFSFDLNGLDAVFFYGDIVSHVCKCG
HNMTLIAADLPCTLHFSLFDDNFCAFCTPKKIFIAACAVDVNVCHSVAVIGDEQIDGKFV
TKFSGDKFDFIVGYGMSFSMSSFELAQLYGLCITPNVCFVKGDIINVARLVKADV----I
VNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMVKSKGVCQVGDCYVST--GGKLCK-TI
LNIVGPDARQDGRQSYVLLARAYKHLNNYDCC--LSTLISAGIFSVPADVSLTYLLGVV-
DKQVILVSNNKEDFDIIQ------------------------------------------
------------------------------------------------------------
-----------------------------------------KCQITSVVGTKALA-----
------VR-------------------------------LTANVGRVIKFETDAYKLFLS
GDDCF---------VSNSSVIQEVLL----------------LRHDIQLNNDVR------
---DYLLSKMTSLP-----------------------------KDWRLINKFDVINGVKT
VKYFECPNSIYICSQGKDFGYVCDGSFYKA----TVNQVCVLLAKK-------IDVLLTV
D------GVNFKSISLTVGEVFGKIL-GNVFCDGIDVTKLKCSDFYADKILYQYENLSLA
DISAVQSSFGFDQQQLLA-YYNFLTVCK-WSVVVNGPFFSFEQSHNNCYVNVACLMLQHI
N-LKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGAI
CELE---LICD-C----GIKQESRVGVDAVMH-FGTLAKTDLFNGYKIGCNCAGRIV-HC
TKLNVPFLICS-----NTPLSKDL--PDDVVAANMFMGVGV---GHYTHLKCGSPY-QHY
DACSVKKYTGVSGCLTDCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYY
TKPIIKAQF--KPFAKVDGVYTNFKLVGHD-------ICAQLNDKLGFNVDLPFV-EYKV
TVWPVATGDVVLASDDLYVKRYFKGCETFGKPVIWLCHDEA----------SLNSLTYFN
KPSFKSENRYSVLSVDSVS---------------------------------------EE
SQGNVVTSVMESQI-STKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDMYL
T-GCDYVVWVANELSRLVKSPT--------------VREYIRYGIK---------PITIP
IDLLCLRDDNQTLLVPKIFKARAIEFYGFLKWLFIYVFSLLHFTNDKTI-----------
-----FYTTEIASKFTFNLFCLALKNAFQTFRWSIFIKGFLVV-----ATVFLFWFNFLY
INVIFSDFYLPNISVFPIFVGRIVMWIKATFGLVTICDFYSKLGVGFT----SHFCNG-S
FICELCYSGFDMLDTYAAIDFV-QYEVDRRVLFDYVSLVKLIVELVIGYSLYTVWFYPLF
CLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANMLPAFVLLRFYIVVTAMYKVVGFIRHI
VYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYYDITANGGTGFCVKHQWNCFNCHSFKP
GNTFITVEAAIELSKELKRPVNPTDASHYVVTDIKQVGCMMRLFY-----DRDGQRVYD-
DVDASLFVDINNLL----HSKVKVVPNLYVVVVE--SDADRANFLNAVVFYAQSLYRPIL
LVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNFVNIAHASLREGVQLEKVL
DTFVGCVRKCC-SIDS-DVETRFITKSMISAVAAGLEFTDENYNNLVPTYLKSDN--IVA
ADLGVLIQNGAKHVQGNVAKAANISCIWFIDTFNQLTADLQHKLKKACVKTGLKLKLTFN
KQEASVPILTTPF--SLK--GG
>DQ339101_CoV-HKU1C_N5_nsp3_2627..8563_5937bp_1979aa
--GRKVNFNEKPVVMEIPS--LMT-VKVMFDLDSTFDDIL-GKVC-SEFEVEKGVTVDDF
VAVVCDAIENALNSC-KEHPVVGYQVRAF-LNKLNENVVYLFDEAGDEAMASR--MYCTF
AI--EDVEDVISSEAVEDTIDGVVEDTINDDEDVVTGDNDDEDVVTGDNDDEDVVTGDND
DE---------------DVVTGDNDDEDVV------------------------------
----------TGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNNDEDVVTGDNNDEESV
TGDNDDQIVVTGDDVDD-IESIYDFDTYKALLVFNDVYNDALFVSYGSSVETETYFKVNG
LWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYK---VGYNQSFVDYLLTTIPK
AIVLPQGGYVADFAYWFLNQFDINAYANWCCLKCGFSFDLNGLDAVFFYGDIVSHVCKCG
HNMTLIAADLPCTLHFSLFDDNFCAFCTPKKIFIAACAVDVNVCHSVAVIGDEQIDGKFV
TKFSGDKFDFIVGYGMSFSMSSFELAQLYGLCITPNVCFVKGDIINVARLVKADV----I
VNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMVKSKGVCQVGDCYVST--GGKLCK-TI
LNIVGPDARQDGRQSYVLLARAYKHLNNYDCC--LSTLISAGIFSVPADVSLTYLLGVV-
DKQVILVSNNKEDFDIIQ------------------------------------------
------------------------------------------------------------
-----------------------------------------KCQITSVVGTKALA-----
------VR-------------------------------LTANVGRVIKFETDAYKLFLS
GDDCF---------VSNSSVIQEVLL----------------LRHDIQLNNDVR------
---DYLLSKMTSLP-----------------------------KDWRLINKFDVINGVKT
VKYFECPNSIYICSQGKDFGYVCDGSFYKA----TVNQVCVLLAKK-------IDVLLTV
D------GVNFKSISLTVGEVFGKIL-GNVFCDGIDVTKLKCSDFYADKILYQYENLSLA
DISAVQSSFGFDQQQLLA-YYNFLTVCK-WSVVVNGPFFSFEQSHNNCYVNVACLMLQHI
N-LKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGAI
CELE---LICD-C----GIKQESRVGVDAVMH-FGTLAKTDLFNGYKIGCNCAGRIV-HC
TKLNVPFLICS-----NTPLSKDL--PDDVVAANMFMGVGV---GHYTHLKCGSPY-QHY
DACSVKKYTGVSGCLTDCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYY
TKPIIKAQF--KPFAKVDGVYTNFKLVGHD-------ICAQLNDKLGFNVDLPFV-EYKV
TVWPVATGDVVLASDDLYVKRYFKGCETFGKPVIWFCHDEA----------SLNSLTYFN
KPSFKSENRYSVLSVDSVS---------------------------------------EE
SQGNVVTSVMESQI-STKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDMYL
T-GCDYVVWVANELSRLVKSPT--------------VREYIRYGIK---------PITIP
IDLLCLRDDNQTLLVPKIFKARAIEFYGFLKWLFIYVFSLLHFTNDKTI-----------
-----FYTTEIASKFTFNLFCLALKNAFQTFRWSIFIKGFLVV-----ATVFLFWFNFLY
INVIFSDFYLPNISVFPIFVGRIVMWIKATFGLVTICDFYSKLGVGFT----SHFCNG-S
FICELCHSGFDMLDTYAAIDFV-QYEVDRRVLFDYVSLVKLIVELVIGYSLYTVWFYPLF
CLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANMLPAFVLLRFYIVVTAMYKVVGFIRHI
VYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYYDITANGGTGFCVKHQWNCFNCHSFKP
GNTFITVEAAIELSKELKRPVNPTDASHYVVTDIKQVGCMMRLFY-----DRDGQRVYD-
DVDASLFVDINNLL----HSKVKVVPNLYVVVVE--SDADRANFLNAVVFYAQSLYRPIL
LVDKKLITTACNGISVTQIMFDVYVDTFMSHFDVDRKSFNNFVNIAHASLREGVQLEKVL
DTFVGCVRKCC-SIDS-DVETRFITKSMISAVAAGLEFTDENYNNLVPTYLKSDN--IVA
ADLGVLIQNGAKHVQGNVAKVANISCIWFIDAFNQLTADLQHKLKKACVKTGLKLKLTFN
KQEASVPILTTPF--SLK--GG
>NC_003045_BCoV_BCoV-ENT_nsp3_2764..8460_5697bp_1899aa
--GRRVTFKEQPTVNEIAS--TPKTIKVFYELDKDFNTIL-NTAC-GVFEVDDTVDMEEF
YAVVIDAIEEKLSPC-KELEGVGAKVSAF-LQKLEDNSLFLFDEAGEEVLASK--LYCAF
TAPEDDDFLEE------------------------------SGVEEDDVEGEETDLTVTS
AGE--------------PCVASEQEESSEI------------------------------
----------------------------LEDTLDDGPCVETSDSQVEEDVEMS-------
-----------------------------DFADLESVIQDYENVCFEFYTTEPEFVKVLD
LYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYK---QQYSQLFVDTLVNKIPA
NIVVPQGGYVADFAYWFLTLCDWQCVAYWKCIKCDLALKLKGLDAMFFYGDVVSHVCKCG
ESMVLIDVDVPFTAHFALKDKLFCAFITKRSVYKAACVVDVNDSHSMAVVDGKQIDDHRV
TSITSDKFDFIIGHGMSFSMTTFEIAQLYGSCITPNVCFVKGDIIKVSKRVKAEV----V
VNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKSKGVCATGDCYVST--GGKLCK-TV
LNVVGPDARTQGKQSYALLERVYKHLNKYDCV--VTTLISAGIFSVPSDVSLTYLLGTA-
EKQVVLVSNNQEDFDLIS------------------------------------------
------------------------------------------------------------
-----------------------------------------KCQITAVEGTKKLA-----
------ER-------------------------------LSFNVGRSIVYETDANKLILS
NDVAF---------VSTFNVLQDVLS----------------LRHDIALDDDAR------
---TFVQSNVDVVP-----------------------------EGWRVVNKFYQINGVRT
VKYFECPGGIDICSQDKVFGYVQQGSFNKA----TVAQIKALFLDK-------VDILLTV
D------GVNFTNRFVPVGESFGKSL-GNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE
DLKAVRSSFNFDQKELLA-YYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSL
N-LKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAI
CDFE---IACK-C----GVKQEQRTGVDAVMH-FGTLSREDLEIGYTVDCSCGKKLI-HC
VRFDVPFLICS-----NTPASVKL--PKGVGSANIFKGDKV---GHYVHVKCEQSY-QLY
DASNVKKVTDVTGNLSDCLYLKNLKQTFKSVLTTYYLDDVKKIEYNPDLSQYYCDGGKYY
TQRIIKAQF--KTFEKVDGVYTNFKLIGHT-------ICDILNAKLGFDSSKEFV-EYKV
TEWPTATGDVVLATDDLYVKRYERGCITFGKPVIWLSHEQA----------SLNSLTYFN
RPLLVDENKFDVLKVDD-----------------------------------------VD
DGGDISESDAKESK-EINIIKLSGVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWL
T-GCRYVVRTANALSMAVNVPT--------------IRKFIKFGMT---------LVSIP
IDLLNLREIKPVFNVVKAVRNKISACFNFIKWLFVLLFGWIKISADNKV-----------
-----IYTTEVASKLTCKLVALAFKNAFLTFKWSVVARGACII-----ATIFLLWFNFIY
ANVIFSDFYLPKIGFLPTFVGKIAQWIKSTFSLVTICDLYSIQDVGFK----NQYCNG-S
IACQFCLAGFDMLDNYKAIDVV-QYEADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLF
ALISIQILTTWLPELFMLSTLHWSVRLLVSLANMLPAHVFMRFYIIIASFIKLFILFRHV
AYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIRYYDVMANGGTGFCSKHQWNCIDCDSYKP
GNTFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQVGCYMRLFY-----ERDGQRTYD-
DVNASLFVDYSNLL----HSKVKGVPNMHVVVVE--NDADKANFLNAAVFYAQSLFRPIL
MVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIATAHSSIKQGTQICKVL
DTFLSCARKSC-SIDS-DVDTKCLADSVMSAVSAGLELTDESCNNLVPTYLKGDN--IVA
ADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKACCKTGLKLKLTYN
KQMANVSVLTTPF--SLK--GG
>NC_001846_MHV_MHV-A59_nsp3_2706..8720_6015bp_2005aa
--GKKVEFNDKPKVRKIPS--TRK-IKITFALDATFDSVL-SKAC-SEFEVDKDVTLDEL
LDVVLDAVESTLSPC-KEHDVIGTKVCAL-LDRLAGDYVYLFDEGGDEVIAPR--MYCSF
SA--PDDEDCVAADVVDA-----------------------DENQDDDAEDSAVLVADTQ
EEDGVAKGQVEADSE--ICVAHTGSQEELA------------------------------
----------EPDAVGSQTPIASAEETEVGEASDREGIAEAKATVCADAVDAC---PDQV
EAFEIEKVEDSILDELQTELNAPADKTYEDVLAFDAVCSEALSAFYAVPSDETH-FKVCG
FYSPAIERTNCWLRSTLIVMQSLPLEFKDLEMQKLWLSYK---AGYDQCFVDKLVKSVPK
SIILPQGGYVADFAYFFLSQCSFKAYANWRCLECDMELKLQGLDAMFFYGDVVSHMCKCG
NSMTLLSADIPYTLHFGVRDDKFCAFYTPRKVFRAACAVDVNDCHSMAVVEGKQIDGKVV
TKFIGDKFDFMVGYGMTFSMSPFELAQLYGSCITPNVCFVKGDVIKVVRLVNAEV----I
VNPANGRMAHGAGVAGAIAEKAGSAFIKETSDMVKAQGVCQVGECYESA--GGKLCK-KV
LNIVGPDARGHGKQCYSLLERAYQHINKCDNV--VTTLISAGIFSVPTDVSLTYLLGVV-
TKNVILVSNNQDDFDVIE------------------------------------------
------------------------------------------------------------
-----------------------------------------KCQVTSVAGTKALS-----
------LQ-------------------------------LAKNLCRDVKFVTNACSSLFS
-ESCF---------VSSYDVLQEVEA----------------LRHDIQLDDDAR------
---VFVQANMDCLP-----------------------------TDWRLVNKFDSVDGVRT
IKYFECPGGIFVSSQGKKFGYVQNGSFKEA----SVSQIRALLANK-------VDVLCTV
D------GVNFRSCCVAEGEVFGKTL-GSVFCDGINVTKVRCSAIYKGKVFFQYSDLSEA
DLVAVKDAFGFDEPQLLK-YYTMLGMCK-WSVVVCGNYFAFKQSNNNCYINVACLMLQHL
S-LKFPKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNEPSDSIDFMRVVLREADLSGAT
CNLE---FVCK-C----GVKQEQRKGVDAVMH-FGTLDKGDLVRGYNIACTCGSKLV-HC
TQFNVPFLICS-----NTPEGRKL--PDDVVAANIFTGGSV---GHYTHVKCKPKY-QLY
DACNVNKVSEAKGNFTDCLYLKNLKQTFSSVLTTFYLDDVKCVEYKPDLSQYYCESGKYY
TKPIIKAQF--RTFEKVDGVYTNFKLVGHS-------IAEKLNAKLGFDCNSPFV-EYKI
TEWPTATGDVVLASDDLYVSRYSSGCITFGKPVVWLGHEEA----------SLKSLTYFN
RPSVVCENKFNVLPVDVSEPTDKGPVPAAVLVTGVPGADASAGAGIAKEQKACASASVED
QVVTEVRQEPSVSAADVKEVKLNGVKKPVKVEGSVVVNDPTSETKVVKSLSIVDVYDMFL
T-GCKYVVWTANELSRLVNSPT--------------VREYVKWGKG---------KIVTP
AKLLLLRDEKQEFVAPKVVKAKAIACYCAVKWFLLYCFSWIKFNTDNKV-----------
-----IYTTEVASKLTFKLCCLAFKNALQTFNWSVVSRGFFLV-----ATVFLLWFNFLY
ANVILSDFYLPNIGPLPTFVGQIVAWFKTTFGVSTICDFYQVTDLGYR----SSFCNG-S
MVCELCFSGFDMLDNYDAINVV-QHVVDRRLSFDYISLFKLVVELVIGYSLYTVCFYPLF
VLIGMQLLTTWLPEFFMLETMHWSARLFVFVANMLPAFTLLRFYIVVTAMYKVYCLCRHV
MYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCTKHQWNCLNCNSWKP
GNTFITHEAAADLSKELKRPVNPTDSAYYSVTEVKQVGCSMRLFY-----ERDGQRVYD-
DVNASLFVDMNGLL----HSKVKGVPETHVVVVE--NEADKAGFLGAAVFYAQSLYRPML
MVEKKLITTANTGLSVSRTMFDLYVDSLLNVLDVDRKSLTSFVNAAHNSLKEGVQLEQVM
DTFIGCARRKC-AIDS-DVETKSITKSVMSAVNAGVDFTDESCNNLVPTYVKSDT--IVA
ADLGVLIQNNAKHVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKTGLKIKLTYN
KQEANVPILTTPF--SLK--GG
>NC_007732_PHEV_VW572_nsp3_2764..8460_5697bp_1899aa
--GKRVTFKEQPTVNEIVS--MPKTIKVFYELDKDFNTIL-NTAC-GVFEVDDTVDMEEF
YAVVIDAIEEKLSPC-KELEGVGAKVSAF-LQKLDDNSLFLFDEAGEEVFAPK--LYCAF
TAPEEDYFLEE------------------------------SDVEEDDVEGEETDLTVTS
AGE--------------PCVASKQKESSEI------------------------------
----------------------------LEDTLDDGPCVETSDSQVEEDVEMS-------
-----------------------------DFVDLESVIQDYENVCFDFYTTEPEFIKVLD
LYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYK---QQYSQLFVDTLVNKIPA
NIVVPQGGYVADFAYWFLTLCDWQCVAYWKCIKCDLALKLKGLDAMFFYGDVVSHVCKCG
ESMVLIDVNVPFTAHFALKDKLFCAFITKRSVYKAACVVDVNDSHSMAVVDGKQIDDHRI
TSITSDKFDFIIGHGMSFSMTTFEIAQLYGSCITPNVCFVKGDIIKVSKRVKAEV----V
VNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKSKGVCATGDCYVST--GGKLCK-TV
LNVVGPDARAQGKQSYALLERVYKHLNKYDCV--VTTLISAGIFSVPSDVSLTYLLGTA-
TKQVVLVSNNQEDFDLIS------------------------------------------
------------------------------------------------------------
-----------------------------------------KCQITAVEGTKKLA-----
------ER-------------------------------LSFNVGRSIVYETDANKLLLS
NEVAF---------VSTFNVLQDVLS----------------LRHDIILEDDAR------
---TFVQSNVDIVP-----------------------------EGWRVVNKFDQINGVRT
VKYFECPGGIDICSQGKVFGYVQRGVFNKA----TVAQIKALFVDK-------VDVLLTV
D------GVNFTNRFIPVSESFGKIL-GNVFCDGVNVTKHKCDIKYKGKVFFQFDNLSSE
ELKAVRSSFNFDQKELLA-YYNMLVNCNKWQVVVNGKYFTFKQANNNCFVNVSCLMLQSL
T-LKFKIVQWQEAWLEFRSGRPARFVALVMAKGGFKFGDPADSRDFLRVVFSQVDLTGAT
CDFE---IACK-C----GVKQEQRTGLDAVMH-FGTLSREELEVGYTVDCSCGKKLI-HC
VRFDVPFLICS-----NTPSSVKL--PKGVVCANIFIGDKV---GHYVHVKCEQAY-QLY
DASNVKKVADVTGNLSDCLYLKNLKQTFKSVLTTYYLDDVKKIEYNPDLSQYYCDGGKYY
TQRIIKAQF--KTFEKVDGVYTNFKLVGHT-------ICDSLNAKLGFDSSKEFV-EYKV
TEWPTATGDVVLATDDLYVKRYERGCITFGKPVIWLSHEKA----------SLNSLTYFN
RPSLVDDNKFAVLKVAD-----------------------------------------VD
SGDDSSESAVKETK-KINIVQLNGVKKPFKVEDSVVINDDTSETKYVKSLSIVDVYDMWL
T-GCKYVVKTANALSRAVNVPT--------------IRKYIKFGMT---------LVSIP
IDLLNLRDIKPVVNVVRAVRNKVSACFNFIKWLFVLLFGWIKISADNKV-----------
-----IYTTEIASKLTCKLVALAVKNALLTFNWSMVARGACII-----ATIFLLWFNFIY
ANVIFSDFYLPKIGFLPTFVGKIAQWIKSTFSLVTICDFYSVQDVGFK----NQYCNG-S
IACQFCLSGFDMLDNYKAIDVV-QYEADRRVVVDYTGVLKIVIELIVSYALYTAWFYPLF
ALISLQILTTWLPELFMLSTLHWSFRLLVSLANMLPAHVFMRFYIIIASFIKLFSLFRHV
AYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIRYYDVMANGGTGFCSKHQWNCIDCDSYKP
GNTFITVEAAFDLSRELKRPIQPTDVAYHTVTDVKQVGCSMRLFY-----DRDGQRTYD-
DVNASLFVDYSNLL----HSKVKSVPNMHVVVVE--NDADKANFLNAAVFYAQSLFRPIL
MVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIVTAHSSIKQGTQIDKVL
DTFLSCARKSC-SIDS-DVGTKCLADSVMSAVSAGLELTDESCNNLVPTYLKGDN--IVA
ADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKACCKTGLKLKLTYN
KQMANVSVLTTPF--SLK--GG
>EF424621_AntelopeCoV_US/OH1/2003WD1418_nsp3_2749..8445_5697bp_1899aa
--GRRVTFKEQPTVNEIAS--TPKTIKVFYELDKDFNTIL-NTAC-GVFEVDDTVDMEEF
YAVVVDAIEEKLSPC-KELEGVGAKVSAF-LQKLEDNSLFLFDEAGEEVLASK--LYCAF
TAPEDDDFLEE------------------------------SGVEEDDVEGEETDLTVTS
AGE--------------PCVASEQEESSEI------------------------------
----------------------------LENTLDDGPCVETSDSQVEEDVEMS-------
-----------------------------DFADLESVIQDYENVCFEFYTTEPEFVKVLD
LYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYK---QQYSQLFVDTLVNKIPA
NIVVPQGGYVADFAYWFLTLCDWQCVAYWKCIKCDLALKLKGLDAMFFYGDVVSHVCKCG
ESMVLIDVDVPFTAHFALKDKLFCAFITKRSVYKAACVVDVNDSHSMAVVDGKQIDDHRV
TSITSDKFDFIIGHGMSFSMTTFEIAQLYGSCITPNVCFVKGDIIKVSKRVKAEV----V
VNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKSKGVCATGDCYVST--GGKLCK-TV
LNVVGPDARTQGKQSYALLERVYKHLNKYDCV--VTTLISAGIFSVPSDVSLTYLLGTA-
EKQVVLVSNNQEDFDLIS------------------------------------------
------------------------------------------------------------
-----------------------------------------KCQITAVEGTKKLA-----
------ER-------------------------------LSFNVGRSIVYETDANKLILS
NDVAF---------VSTFNVLQDVLS----------------LRHDIALDDDAR------
---TFVQSNVDVVP-----------------------------EGWRVVNKFYQINGVRT
VKYFECPGGIDICSQDKVFGYVQQGSFNKA----TVAQIKALFLDK-------VDILLTV
D------GVNFTNRFVSVGESFGKSL-GNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE
DLKAVRSSFNFDQKELLA-YYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSL
N-LKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAI
CDFE---IACK-C----GVKQEQRTGVDAVMH-FGTLSREDLEIGYTVDCSCGKKLI-HC
VRFDVPFLICS-----NTPASVKL--PKGVGSANIFKGDKV---GHYVHVKCEQSY-QLY
DASNVKKVTDVTGNLSDCLYLKNLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYY
TQRIIKAQF--KTFEKVDGVYTNFKLIGHT-------ICDILNAKLGFDSSKEFV-EYKV
TEWPTATGDVVLATDDLYVKRYERGCITFGKPVIWLSHEQA----------SLNSLTYFN
RPLLVDENKFDVLKVDD-----------------------------------------VD
DGGDISESDAKESK-EINIIKLSGVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWL
T-GCRYVVRTANALSMAVNVPT--------------IRKFIKFGMT---------LVSIP
IDLLNLREIKPVFNVVKAMRNKISACFNFIKWLFVLLFGWIKISADNKV-----------
-----IYTTEVASKLTCKLVALAFKNAFLTFKWSVVARGACII-----ATIFLLWFNFIY
ANVIFSDFYLPKIGFLPTFVGKIAQWIKSTFSLVTICDLYSIQDVGFK----NQYCNG-S
IACQFCLAGFDMLDNYKAIDVV-QYEADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLF
ALISIQILTTWLPELFMLSTLHWSVRLLVSLANMLPAHVFMRFYIIIASFIKLFSLFRHV
AYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIRYYDVMANGGTGFCSKHQWNCIDCDSYKP
GNTFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQVGCYMRLFY-----ERDGQRTYD-
DVNASLFVDYSNLL----HSKVKGVPNMHVVVVE--NDADKANFLNAAVFYAQSLFRPIL
MVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIATAHSSIKQGTQICKVL
DTFLSCARKSC-SIDS-DVDTKCLADSVMSAVSAGLELTDESCNNLVPTYLKGDN--IVA
ADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKACCKTGLKLKLTYN
KQMANVSVLTTPF--SLK--GG
>EF424622_GiCoV_US/OH3-TC/2006_nsp3_2748..8444_5697bp_1899aa
--GRRVTFKEQPTVNEIAS--TPKTIKVFYELDKDFNTIL-NTAC-GVFEVDDTVDMEEF
YAVVVDAIEEKLSPC-KELEGVGAKVSAF-LQKLEDNSLFLFDEAGEEVLASK--LYCAF
TAPEDDDFLEE------------------------------SGVEEDDVEGEETDLTVTS
AGE--------------PCVASEQEESSEI------------------------------
----------------------------LENTLDDGPCVETSDSQVEEDVEMS-------
-----------------------------DFADLESVIQDYENVCFEFYTTEPEFVKVLD
LYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYK---QQYSQLFVDTLVNKIPA
NIVVPQGGYVADFAYWFLTLCDWQCVAYWKCIKCDLALKLKGLDAMFFYGDVVSHVCKCG
ESMVLIDVDVPFTAHFALKDKLFCAFITKRSVYKAACVVDVNDSHSMAVVDGKQIDDHRV
TSITSDKFDFIIGHGMSFSMTTFEIAQLYGSCITPNVCFVKGDIIKVSKRVKAEV----V
VNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKSKGVCATGDCYVST--GGKLCK-TV
LNVVGPDARTQGKQSYALLERVYKHLNKYDCV--VTTLISAGIFSVPSDVSLTYLLGTA-
EKQVVLVSNNQEDFDLIS------------------------------------------
------------------------------------------------------------
-----------------------------------------KCQITAVEGTKKLA-----
------ER-------------------------------LSFNVGRSIVYETDANKLILS
NDVAF---------VSTFNVLQDVLS----------------LRHDIALDDDAR------
---TFVQSNVDVVP-----------------------------EGWRVVNKFYQINGVRT
VKYFECPGGIDICSQDKVFGYVQQGSFNKA----TVAQIKALFLDK-------VDILLTV
D------GVNFTNRFVSVGESFGKSL-GNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE
DLKAVRSSFNFDQKELLA-YYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSL
N-LKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAI
CDFE---IACK-C----GVKQEQRTGVDAVMH-FGTLSREDLEIGYTVDCSCGKKLI-HC
VRFDVPFLICS-----NTPASVKL--PKGVGSANIFKGDKV---GHYVHVKCEQSY-QLY
DASNVKKVTDVTGNLSDCLYLKNLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYY
TQRIIKAQF--KTFEKVDGVYTNFKLIGHT-------ICDILNAKLGFDSSKEFV-EYKV
TEWPTATGDVVLATDDLYVKRYERGCITFGKPVIWLSHEQA----------SLNSLTYFN
RPLLVDENKFDVLKVDD-----------------------------------------VD
DGGDISESDAKESK-EINIIKLSGVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWL
T-GCRYVVRTANALSMAVNVPT--------------IRKFIKFGMT---------LVSIP
IDLLNLREIKPVFNVVKAMRNKISACFNFIKWLFVLLFGWIKISADNKV-----------
-----IYTTEVASKLTCKLVALAFKNAFLTFKWSVVARGACII-----ATIFLLWFNFIY
ANVIFSDFYLPKIGFLPTFVGKIAQWIKSTFSLVTICDLYSIQDVGFK----NQYCNG-S
IACQFCLAGFDMLDNYKAIDVV-QYEADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLF
ALISIQILTTWLPELFMLSTLHWSVRLLVSLANMLPAHVFMRFYIIIASFIKLFSLFRHV
AYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIRYYDVMANGGTGFCSKHQWNCIDCDSYKP
GNTFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQVGCYMRLFY-----ERDGQRTYD-
DVNASLFVDYSNLL----HSKVKGVPNMHVVVVE--NDADKANFLNAAVFYAQSLFRPIL
MVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIATAHSSIKQGTQICKVL
DTFLSCARKSC-SIDS-DVDTKCLADSVMSAVSAGLELTDESCNNLVPTYLKGDN--IVA
ADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKACCKTGLKLKLTYN
KQMANVSVLTTPF--SLK--GG
>NC_004718_SARS-human_Tor2_nsp3_2719..8484_5766bp_1922aa
APIKGVTFGED-TVWEVQG--YKN-VRITFELDERVDKVL-NEKC-SVYTVESGTEVTEF
ACVVAEAVVKTLQPVSDLLTNMGIDLDEWSVATF-----YLFDDAGEENFSSR--MYCSF
YP--PDEEE--------------------------------EDDAECEEEEID-------
-----------------ETCEHEYGTEDDY------------------------------
-------------------------QGLPLEFGASAETVRVEEEEEEDWLDDT-------
------------------------------------------------------------
---------------------------------------------TEQSEIEPEPEPTPE
EPVNQFTGYL--------------------------------------------------
------------------------------------------------------------
-------------------------------KLTDNVAIKCVDIVKEAQSANPMV----I
VNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLS--GHNLAK-KC
LHVVGPNLNAG--EDIQLLKAAYENFNSQDIL--LAPLLSAGIFGAKPLQSLQVCVQTV-
RTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPK
IKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVI
TSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKS
AFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKI
QEGIVD-YGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLK
APAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETV--SLAGSYRDW----SYSGQRTELG
VEFLKRGDKIVYHTLESPVEFHLDGEVL------SLDKLKSLLSLR---EVKTIKVFTTV
D------NTNLHTQLVDMSMTYGQQF-GPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTL
RSEAF-EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQL
E-VKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAK
RVLN---VVCKHC----GQKTTTLTGVEAVMY-MGTLSYDNLKTGVSIPCVCGRDATQYL
VQQESSFVMMS-----APPAEYKL-QQGTFLCANEYTGNYQC--GHYTHITAKETL-YRI
DGAHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYY
TEQPIDLV---PTQPLPNASFDNFKL-----TCSNTKFADDLNQMTGF--TKPASRELSV
TFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCL--WS
TKPVDTSNSFEVLAVEDTQGMDNLA---------------------------------CE
SQQPTSEEVVENPT-IQKEVIECDVKTTEVVGNVILKPSDEG-VKVTQELGHEDLMAAYV
E-NTSITIKKPNELSLALGLKT-----------------IATHGIAAINSVPWSKILAYV
KPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNS--------RIRASL
PTTIAKNSVKSVA----KLCLDAGINYVKSPKFSK-------------LFTIAMWLLLLS
ICLG-SLICVTA----AFGVLL------SNFGAPSYCNGVRELYLNSSNVTTMDFCEG-S
FPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILG---LAAEWVLAYMLFTKFFYLLG
LSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHI
MDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCT
GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYF-----DKAGQKTYE-
RHPLSHFVNLDNLR----ANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPIL
LLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVL
STFVSAARQG--VVDT-DVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVEN--MTP
RDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCA
TTRQVVNVITTKI--SLK--GG
>AY304488_SARS-civet_SZ16_nsp3_2704..8469_5766bp_1922aa
APIKGVTFGED-TVWEVQG--YKN-VRITFELDERVDRVL-NEKC-SVYTVESGTEVTEF
ACVVAEAVVKTLQPVSDLLTNMGIDLDEWSVATF-----YLFDDAGEENFSSR--MYCSF
YP--PDEEE--------------------------------EDDAECEEEEID-------
-----------------ETCEHEYGTEDDY------------------------------
-------------------------QGLPLEFGASAETVRVEEEEEEDWLDDT-------
------------------------------------------------------------
---------------------------------------------TEQSEIEPEPEPTPE
EPVNQFTGYL--------------------------------------------------
------------------------------------------------------------
-------------------------------KLTDNVAIKCADIVKEAQSANPMV----I
VNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLS--GHNLAK-KC
LHVVGPNLNAG--EDIQLLKAAYENFNSQDTL--LAPLLSAGIFGAKLLQSLQVCVQTV-
RTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPK
IKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVI
TSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKS
AFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKI
QEGIVD-YGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLK
APAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETV--SLAGSYRDW----SYSGQRTELG
VEFLKRGDKIVYHTLESPVEFHLDGEVL------SLDKLKSLLSLR---EVKTIKVFTTV
D------NTNLHTQLVDMSMTYGQQF-GPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTL
RSEAF-EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQI
E-VKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAK
RVLN---VVCKHC----GQKTTTLTGVEAVMY-MGTLSYDNLKTGVSIPCVCGRDATQYL
VQQESSFVMMS-----APPAEYKL-QQGTFLCANEYTGNYQC--GHYTHITAKETL-YRI
DGAHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYY
TEQPIDLV---PTQPLPNASFDNFKL-----TCSNTKFADDLNQMTGF--TKPASRELSV
TFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCL--WS
TKPVDTSNSFEVLAVEDTQGMDNLA---------------------------------CE
SQQPTSEEVVENPT-IQKEVIECDVKTTEVVGNVILKPSDEG-VKVTQELGHEDLMAAYV
E-NTSITIKKPNELSLALGLKT-----------------IATHGIAAINSVPWSKIFAYV
KPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNS--------RIRASL
PTTIAKNSVKSVA----KLCLDAGINYVKSPKFSK-------------LFTIAMWLLLLS
ICLG-SLIYVTA----AFGVLL------SNFGAPSYCNGVRELYLNSSNVTTMDFCEG-S
FPCSICSSGLDSLDSYPALETIQVTISSYKLDLTILG---LAAEWVLAYMLFTKFFYLLG
LSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHI
MDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCT
GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYF-----DKAGQKTYE-
RHPLSHFVNLDNLR----ANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPIL
LLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVL
STFVSAARQG--VVDT-DVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVEN--MTP
RDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCA
TTRQVVNVITTKI--SLK--GG
>NC_009694_SARS-bat_HKU3-1_nsp3_2716..8463_5748bp_1916aa
APVKGVTFGED-TVLEVQG--YKN-VKITFELDVRVDKVL-NEKC-SVYTVESGTEVTEF
ACVVAEAVVKTLQPVSDLLTPMGIDLDEWSVATF-----YLFDDAGEEKLSSR--MYCSF
YP--PDEE---------------------------------EDCEECEDEE---------
-----------------ETCEHEYGTEDDY------------------------------
-----------------------KGLPLEFGASTETPH-VEEEEEEEDWLDDA-------
------------------------------------------------------------
------------------------------------------------IEAEPEPEPLPE
EPVNQFVGYL--------------------------------------------------
------------------------------------------------------------
-------------------------------KLTDNVAIKCIDIVKEAQSAKPTV----I
VNAANTHLKHGGGVAGALNKATNGAMQNESDEYIRQNGPLTVGGSCLLS--GHNLAE-KC
LHVVGPNLNAG--EDVQLLKRAYENFNSQDVL--LAPLLSAGIFGAKPLQSLKMCVEIV-
RTQVYLAVNDKSLYDQIVLDYLDSLKPKVESPNKEEEPKLEEPKAVQP-VAEKPVDVKPK
IKACIDEVTTTLEETKFLTNKLLLFADINGKLYQDSQNMLRGEDMSFLEKDAPYIVGDVI
TSGDITCVIIPAKKSGGTTEMLARALKEVPVAEYITTYPGQGCAGYTLEEAKTALKKCKS
AFYVLPSETPNEKEEVLGTVSWNLREMLAHAEETRKLMPICLDVRAIMATIQRKYKGIKV
QEGIVD-YGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGLNLEEAARCMRSLK
APAVVSVSSPDAVTAYNGYLTSSSKTPEEYFVETT--SLAGSYRDW----SYSGQRTELG
VEFLKRGDKIVYHTTGSPIEFHLDGEVL------PLDKLKSLLSLR---EVKTIKVFTTV
D------NTNLHTHIVDMSMTYGQQF-GPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTL
RSEAF-EYYHTIDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQV
E-VKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAK
RVLN---VVCKHC----GQKTTTLKGVEAVMY-MGTLSYDELKTGVSIPCVCGRNATQYL
VQQESSFVMMS-----APPAEYKL-QQGAFLCANEYTGNYQC--GHYTHITAKETL-YRV
DGAHLTKMSEYKGPVTDVFY-KETSYTTAIKPVSYKLDGVTYTEIEPKLDGYYKKGNAYY
TEQPIDLV---PTQPMPNASFDNFKL-----TCSNTKFADDLNQMTGF--KKPASRELTV
TFFPDLNGDVVAIDYRHYSTSFKKGAKLVHKPILWHINQTTNKTTYKPNIWCLRCL--WS
TKPVDTSNSFEVLVVEDTQGMDNLA---------------------------------CE
SQTTTSEEVVENPT-VQKEIIECDVKTTEVVGNVILKPSEEG-VKVTQELGHEDLMAAYV
E-ETSITIKKPNELSLALGLKT-----------------LATHGAAAINSVPWSKILAYV
KPFLGQTAVITSNCIKKCVQRVFSNYMPYVITLLFQLCTFTKSTNS--------RIKASL
PTTIAKNSVKSVA----KLCLDVCINYVKSPKFSK-------------LFTIVMWLLLLS
ICLG-SLTYVTA----VLGVCL------SSLGVPSYCDGVRELYINSSNVTTMDFCQG-Y
FPCSVCLSGLDSLDSYPALETIQVTISSYKLDLTFLG---LAAEWLLAYMLFTKFFYLLG
LSAIMQAFFGYFASHFISNS--WLMWFIISIVQMAPVSAMVRMYIFFASFYYVWKSYVHI
MDGCTSSTCMMCYKRNRATRVECTTIVNGVKRSFYVYANGGRGFCKAHNWNCLNCDTFCA
GSTFISDEVARDLSLQFKRPINPTDQSAYVVDSVTVKNGALHLYF-----DKAGQKTYE-
RHPLSHFVNLDNLR----ANNTKGSLPINVIVFDGKSKCEESAAKSASVYYSQLMCQPIL
LLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVL
STFVSAARQG--VVDT-DVDTKDVIECLKLSHHSDIEVTGDSCNNFMLTYNKVEN--MTP
RDLGACIDCNARHINAQVAKSHNVSLVWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCA
TTRQVVNVITTKI--SLK--GG
>AY545919_SARS-badger_CFB/SZ/94/03_nsp3_2698..8463_5766bp_1922aa
APIKGVTFGED-TVFEVQG--YKN-VRITFELDERVDKVL-NEKC-SVYTVESGTEVTEF
ACVVAEAVVKTLQPVSDLLTNMGIDLDEWSVATF-----YLFDDAGEENFSSR--MYCSF
YP--PDEEE--------------------------------EDDAECEEEEID-------
-----------------ETCEHGYGTEDDY------------------------------
-------------------------QGLPLEFGASAETVRVEEEEEEDWLDDT-------
------------------------------------------------------------
---------------------------------------------TEQSEIEPEPEPTPE
EPVNQFTGYL--------------------------------------------------
------------------------------------------------------------
-------------------------------KLTDNVAIKCVDIVKEAQSANPMV----I
VNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLS--GHNLAK-KC
LHVVGPNLNAG--EDIRLLKAAYENFNSQDTL--LAPLLSAGIFGAKPLQSLQVCVQTV-
RTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPK
IKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVI
TSGDITCVVIPSKKTGGTTEMLSRALKKVPVAEYITTYPGQGCAGYTLEEAKTALKKCKS
AFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKI
QEGIVD-YGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLK
APAIVSVSSPDAVTTYNGYLTSSSKTSEEHFVETV--SLAGSYRDW----SYSGQRTELG
VEFLKRGDKIVYHTLESPVEFHLDGEVL------SLDKLKSLLSLR---EVKTIKVFTTV
D------NTNLHTQLVDMSMTYGQQF-GPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTL
RSEAF-EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQI
E-VKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAK
RVLN---VVCKHC----GQKTTTLTGVEAVMY-MGTLSYDNLKTGVSIPCVCGRDATQYL
VQQESSFVMMS-----APPAEYKL-QQGTFLCANEYTGNYQC--GHYTHITAKETL-YRI
DGAHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYY
TEQPIDLV---PTQPLPNASFDNFKL-----TCSNTKFADDLNQMTGF--TKPASRELSV
TFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCL--WS
TKPVDTSNSFEVLAVEDTQGMDNLA---------------------------------CE
SQQPTSEEVVENPT-IQKEVIECDVKTTEVVGNVILKPSDEG-VKVTQELGHEDLMAAYV
E-NTSITIKKPNELSLALGLKT-----------------IATHGIAAINSVPWSKILAYV
KPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNS--------RIRASL
PTTIAKNSVKSVA----KLCLDAGINYVKSPKFSK-------------LFTIAMWLLLLS
ICLG-SLICVTA----AFGVLL------SNFGAPSYCNGVRELYLNSSNVTTMDFCEG-S
FPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILG---LAAEWVLAYMLFTKFFYLLG
LSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHI
MDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCT
GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYF-----DKAGQKTYE-
RHPLSHFVNLDNLR----ANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPIL
LLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVL
STFVSAARQG--VVDT-DVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVEN--MTP
RDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCA
TTRQVVNVITTKI--SLK--GG
>NC_009019_Bat-CoV-HKU4_B04f HKU41_nsp3_2808..8618_5811bp_1937aa
MPSKKVTFGDV-NTVEVTA--YRS-VSITYDIHPVLDALLSSSKL-ATFTVEKDLLVEDF
VDVIKDEVLTLLTPL-----LRGYDIDGFDVEDFIDVPCYVYNQDGDCAWSSN--MTFSI
NPVEDVEEV--------------------------------EEFIEDDYLSDELPIADDE
EAWA-------------RAVEEVMPLDDIL------------------------------
----------------VAEIELEEDPPLETALESVEAEVVETAEAQEPSVESI-------
---------------------------------------DSTPSTSTVVGENDLSVKPM-
---SRVAETDDVLELETAVVGGPVSDVTAIVTND--IVSV---EQAQQCGVSSLP--IQD
EASENQVHQVSDL--------------------------------------------QGN
ELLCSETKVEIVQPRQDLKPRR-----SRKSKVDLSKYKHT-------------------
-------------------------------VINNSVTLVLGDAIQIASLLPKCI----L
VNAANRHLKHGGGIAGVINKASGGDVQEESDEYISNNGPLHVGDSVLLK--GHGLAD-AI
LHVVGPDARNN--EDAALLKRCYKAFNKHTIV--VTPLISAGIFSVDPKVSFEYLLANV-
TTTTYVVVNNEDIYNTLA------------------------------------------
------------------------------------------------------------
----------------------------TPSKPDGLVYSFEGWRGTVRTAKNYGF-----
------TCF------------------------------ICTEYSANVKFLRTKGVDTTK
KIQTVD--GVSYYLYSARDALTDVIA-AANGCSGICAMPFGYVTHGLDLAQSGNYVRQVK
VPYVCLLASKEQIPIMNS--DVAIQTPETAFINNV--TSNGGYHSWHLVSGDLIVKDVCY
KKLLHWSGQTICYADNKFYVVKNDVALPFS----DLEACRAYLTSR-AAQQVNIEVLVTI
D------GVNFRTVILNDTTTFRKQL-GATFYKGVDISDAFPTVKMGGESLFVADNLSES
EKVVLKEYYGTSDVTFLQRYYSLQPLVQQWKFVVHDGVKSLKLSNYNCYINATIMMIDML
HDIKFVVPALQNAYLRYKGGDPYDFLALIMAYGDCTFDNPDDEAKLLHTLLAKAELTVSA
KMVW--REWCTVC----GIRDIEYTGMRACVY-AGVNSMEELQSVFNETCVCGSVKHRQL
VEHSAPWLLVSG----LNEVKVSTSTDPIYRAFNVFQGVETS-VGHYVHIRVKDGLFYKY
DSGSLTKTSDMKCKMTSVWY-PTVRYTADCNVVVYDLDGVTKVEVNPDLSNYYMKDGKYY
TSKPTIKYS--PATILPGSVYSNSCLVGVDGTPGSDTISKFFNDLLGFDETKPISKKLTY
SLLPNEDGDVLLSEFSNYNPVYKKGVMLKGKPILWVNNGVCDSALNKPNRASLRQL--YD
VAPIVLDNKYTVLQDNTSQL--------------------------------------VE
HNVPVVDDVPITTR-KLIEVKCKGLNKPFVKGNFSFVNDPNG-VTVVDTLGLTELRALYV
DINTRYIVLRDNNWSSLFKLHTVESGDLQIVAAGGSVTRRARVLLGASSLFASFAKITVT
ATTAACKTAGRGFCKFVVNYGVLQNMFVFLKMLFFLPFNYLWPKKQPTV-----DIGVSG
LRTAGIVTTNIVKQCG-TAAYYMLLGKFKRVDWKATLRLFLLLCTTILLLSSIYH-LVLF
NQVLSSDVMLED----ATGILAIYKEVRSYLGIRTLCDGLVVEYRNTS-FDVMEFCSNRS
VLCQWCLIGQDSLTRYSALQMLQTHITSY--VLNIDWIW-FALEFFLAYVLYTSSFNVLL
LVVTAQYFFAYTSAFVNWRAYNYIVSGLFFLVTHIPLHGLVRVYNFLACLWFLRKFYSHV
INGCKDTACLLCYKRNRLTRVEASTIVCGTKRTFYIAANGGTSYCCKHNWNCVECDTAGV
GNTFICTEVANDLTTTLRRLIKPTDQSHYYVDSVVVKDAVVELHY-----NRDGSSCYE-
RYPLCYFTNLEKLKFKEVCKTPTGIPEHNFLIYDTNDRGQENLARSACVYYSQVLCKPML
LVDVNLVTTVGDSREIAIKMLDSFINSFISLFSVSRDKLEKLINTARDCVRRGDDFQNVL
KTFTDAARGHA-GVES-DVETTMVVDALQYAHKNDIQLTTECYNNYVPGYIKPDS--INT
LDLGCLIDLKAASVNQTSMRNANGACVWNSGDYMKLSDSFKRQIRIACRKCNIPFRLTTS
KLRAADNILSVKF--SATKIVG
>NC_009020_Bat-CoV-HKU5_LMH3f HKU51_nsp3_2814..8750_5937bp_1979aa
APPKGVKFGGE-QTKEITA--VRS-VSVDYDVHPVLDALLAGSEL-ATFTVEKDLPVKDF
VDVVKDEVIELLSKL-----LRGYNVDGFDLEDFADTPCYVYNAEGDLAWSST--MTFSV
NPVEEVEEECD------------------------------DDYVEDEYLSEEMLVEEDE
NSWA-------------AAVEAVIPMEDVQ------------------------------
----------------LDTLVAEIDVSEPADDVAEQASTEEVEVPSACVLEAS-------
---------------------------QVANAAEVESCEAEVSSSIPLHEDANAAKANDC
AEGMPALDSTETVSKLSVDTPVGDVTQDDATSSNATVISEDVHTATHSKGLVAVPEVVPE
KALGTSVERMRSTSEWTVVETSL-----------------------------------KQ
ETAVIVKNDSSAKPQRVKKP---------KAENPLKNFKHI-------------------
-------------------------------VLNNDVTLVFGDAIAVARATEDCI----L
VNAANTHLKHGGGIAAAIDRASGGLVQAESDDYVNFYGPLNVGDSTLLK--GHGLAT-GI
LHVVGPDARAN--QDIQLLKRCYKAFNKYPLV--VSPLISAGIFCVEPRVSLEYLLSVV-
HTKTYVVVNSEKVYNDLA------------------------------------------
------------------------------------------------------------
----------------------------APKPPTGLTYSHEGWRGIIRNAKSFGF-----
------TCF------------------------------ICTDQSANAKLLKGRGVDLTK
KTQTVD--GVKYYLYSSKDPLTDIIT-AANACKGICAMPIGYVTHGLDLAQAGQQVKKIT
VPYVCLLASKDQVPILNS--DVAVQTPEQSFINTV--IANGGYHCWHLVTGELIVKGVSY
RKLLNWSDQTICYADNKFYVVKGQIALPFD----SLEKCRTYLTSR-AAQQKNVDVLVTI
D------GVNFRTVVLNNTTTYRVQL-GSVFYKGSDISDTIPTEKMSGEAVYLADNLSEA
EKAVLSEVYGTADTAFLHRYYSLLALVKKWKYTVHDGVKSLKLNSNNCYVNVTMLMLDML
KEIKFIVPALQAAYLKHKGGDSTEFIALIMAYGDCTYGEPDDASRLLHTILSKAELTTQA
KMVW--RQWCNVC----GVQDTTTTGLKACIY-VGMNSLDELHATHEECCQCGDVRKRQL
VEHNAPWLLLSGLNEAKVMTPTSQSAGPDYTAFNVFQGVETS-VGHYLHVRVKDNLLYKY
DSGSLSKTSDMKCKMTDVYY-PKQRYSADCNVVVYSLDGNTWADVDPDLSAFYMKDGKYF
TKKPVIEYS--PATILSGSVYTNSCLVGHDGTIGSDAISSSFNNLLGFDNSKPVSKKLTY
SFFPDFEGDVILTEYSTYDPIYKNGAMLHGKPILWVNNSKFDSALNKFNRATLRQV--YD
IAPVTLENKYTVLQDNQIQQVEV-------------------------------EAPKED
AKPQSPVQVAEDIDNKLPIIKCKGLKKPFVKDGYSFVNDPQG-VNVIDTLGIDDLRALYV
DRNLRLIVLKENNWSALFNIHTVEKGDLSVIAASGSITRRVKILLGASSLFAQFASVTVN
VTTAMGKALGRMTRNVITNTGIIGQGFALLKMLLILPFTFWKSKNQSTV-----KVEVGA
LRTAGIVTTNVVKQCA-SAAYDVLVVKFKRIDWKSTLRLLFLICTTGLLLSSLYY-LFLF
HQVLTSDVMLDG----AEGMLATYRELRSYLGIHSLCDGMVEAYRNVS-YDVNDFCSNRS
ALCNWCLIGQDSLTRYSAFQMIQTHVTSY--VINIDWVW-FVMEFALAYVLYTSTFNVLL
LVVSSQYFFSYTGAFVNWRSYNYLVSGYFFCVTHIPLLGLVRIYNFLACLWFLRRFYNHV
INGCKDTACLLCYKRNRLTRVEASTVVCGSKRTFYIVANGGTSFCCRHNWNCVDCDTAGI
GNTFICEEVANDLTTSLRRLVKPTDKSHYYVESVTVKDSVVQLHY-----SREGASCYE-
RYPLCYFTNLDKLKFKEVCKTPTGIPEHNFLIYDSSDRGQENLARSACVYYSQVLSKPML
LVDSNMVTTVGDSREIASKMLDSYVNSFISLFGVNRDKLDKLVATARDCVKRGDDFQTVI
KTFTDAARGPA-GVES-DVETSSIVDALQYAYKHDLQLTTEGFNNYVPSYIKPDS--VAT
ADLGCLIDLNAASVNQTSIRNANGACIWNSSDYMKLSDSLKRQIRIACRKCNIPFRLTTS
RLRSADNILSVKF--SATKLSG
>NC_009021_Bat-CoV-HKU9_BF_005I HKU91_nsp3_2545..8055_5511bp_1837aa
-GVSKVTFGDE-EVHTIPN--TVT-VNFSYDVCEGLDAIL-DKVM-APFQVEEGTKLEDL
ACVVQKAVYERLSDL---FSDCPAELRPINLEDFLTSECFVYSKDYEKILMPE--MYFSL
EDAVPVDD----------------------------------------------------
-----------------EMVDDIEDTVEQA------------------------------
------------------------------------------SDSDDQWLGDE-------
------------------------------------------------------------
--------------------------------------------GAEDCDNTIQDVDVAT
SMTTP-----------------------------------------------------CG
YT----------------------------------------------------------
-------------------------------KIAEHVYIKCADIVQEARNYSYAV----L
VNAANVNLHHGGGVAGALNRATNNAMQKESSEYIKANGSLQPGGHVLLS--SHGLASHGI
LHVVGPDKRLG--QDLALLDAVYAAYTGFDSV--LTPLVSAGIFGFTVEESLCSLVKNV-
ACTTYVVVYDRQLYERALATSFDVPGPQSSVQHVPAIDWAEAVEVQESIVDQVETPSLGA
VDTVDSNADSGLNETARSPENVVGS-----------------------------------
VPDDVVADVESCVRDLVRQVVKKVKRDKRPPPIVPQQTVEQQPQEISSPGDCNTVLVDVV
SMSFSAMVNFGKEKG------------------------LLIPVVIDYPAFLKVLKRFSP
KEGLFSSNGYEFYGYSRDKPLHEVSKDLNSLGRPLIMIPFGFIVNGQTLAVSAVSMRGLT
VPHTVVVPSESSVPLYRAYFNGVFSGDTTAVQDFVVDILLNGARDWDVLQTTCTVDRKVY
KTICKRGNTYLCFDDTNLYAITGDVVLKFA----TVSKARAYLETKLCAPEPLIKVLTTV
D------GINYSTVLVSTAQSYRAQI-GTVFCDGHDWSNKNPMPTDEGTHLYKQDNFSSA
EVTAIREYYGVDDSNIIARAMSIRKTVQTWPYTVVDGRVLLAQRDSNCYLNVAISLLQDI
D-VSFSTPWVCRAYDALKGGNPLPMAEVLIALGKATPGVSDDAHMVLSAVLNH----GTV
TARRVMQTVCEHC----GVSQMVFTGTDACTF-YGSVVLDDLYAPVSVVCQCGRPAIRYV
SEQKSPWLLMS-----CTPTQVPLDTSGIWKTAIVFRGPVTA--GHYM-YAVNGTLISVY
DANTRRRTSDLKLPATDILY-GPTSFTSDSKVETYYLDGVKRTTIDPDFSKYVKRGDYYF
TTAPIEVVAAPKLVTSYDGFYLSSCQ--------NPQLAESFNKAINATKTGPMK---LL
TMYPNVAGDVVAISDDNVVA-HPYGSLHMGKPVLFVTRPNT----------WKKLVPLLS
TVVVNTPNTYDVLAVDPLPVNN------------------------------------ET
SEEPISVKAP---------IPLYGLKATMVLNGTTYVPGNKGHLLCLKEFTLTDLQTFYV
EGVQPFVLLKASHLSKVLGLRVSDSSLH--------VNHLSKGVVYAYAATRLTTRVTTS
LLGGLVTRSVRKTADFVRSTNPGSKCVGLLCLFYQLFMRFWLLVKKP-----------PI
VKVSGIIAYNTGCGVT-TCVLNYLRSRCGNISWSRLLK----------LLRYMLYIWFVW
TCLTICGVWLSE----PYAPSLVTR-FKYFLGIVMPCDYVLVNETGTG------------
WLHHLCMAGMDSLD-YPALRMQQHRYGSP---YNYTYIL-MLLEAFFAYLLYTPALPIVG
ILAVLHLIVLYLPIPLGNS---WLVVFLYYIIRLVPFTSMLRMYIVIAFLWLCYKGFLHV
RYGCNNVACLMCYKKNVAKRIECSTVVNGVKRMFYVNANGGTHFCTKHNWNCVSCDTYTV
DSTFICRQVALDLSAQFKRPIIHTDEAYYEVTSVEVRNGYVYCYF-----ESDGQRSYE-
RFPMDAFTNVSKLHY---SELKGAAPAFNVLVFDATNRIEENAVKTAAIYYAQLACKPIL
LVDKRMVGVVGDDATIARAMFEAYAQNYLLKYSIAMDKVKHLYSTALQQISSGMTVESVL
KVFVGSTRAEAKDLES-DVDTNDLVSCIRLCHQEGWEWTTDSWNNLVPTYIKQDT--LST
LEVGQFMTANAKYVNANIAKGAAVNLIWRYADFIKLSESMRRQLKVAARKTGLNLLVTTS
SLKADVPCMVTPF--KI---IG
>NC_001451_IBV_Beaudette_nsp3_2548..7323_4776bp_1592aa
--GKTVTFGET-TVQEIPPPDVVP-IKVSIECCGEPWNTIFKKAYKEPIEVDTDLTVEQL
LSVIYEKMCDDLKLF-----PEAPEPPPF--------ENVALVDKNGKDLDCIKSCHLIY
RDYESDDDIEE------------------------------EDAEECDTDSGEAEECDTN
S----------------ECEEEDEDTKVLA------------------------------
--------------LIQDPASIKYPLPLDEDYSVYNGCIVHKDALDVVNLPSG-------
---------EETFVVNN---------------CFEGAVKPLPQKVVDVLGDWGEAVDAQE
QLCQQEPLQHTFEEPVENSTGSSKTMTEQVVVEDQEL-PV---VEQDQDVVVYTPTDLEV
AKETAEE--VDEFILIFAVPKEEVVSQ-------------------------------KD
GAQIKQEPIQVVKPQREKKAKK-------FKVKPATCEKPK-------------------
-------------------------------FLEYKTCV--GDLTVVIAKALDEFKEFCI
VNAANEHMTHGSGVAKAIADFCGLDFVEYCEDYVKKHGPQQ---RLVTPSFVKGIQ--CV
NNVVGP--RHGDNNLHEKLVAAYKNVLVDGVVNYVVPVLSLGIFGVDFKMSIDAMREAFE
GCTIRVLLFSLSQ-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------EHIDYFDVTCK
QK----------------------------------------------------TIYLTE
D------GVKYRSIVLKPGDSLGQF--GQVYAKNKIV---FTADDVEDKEILYVPTTD--
--KSILEYYGLDAQKY---VIYLQTLAQKWNVQYRDNFLILEWRDGNCWISSAIVLLQAA
K-IRFKGF-LTEAWAKLLGGDPTDFVAWCYASCTAKVGDFSDANWLLANLAEHFDADYTN
AFLK-KRVSCN-C----GIKSYELRGLEACIQPVRATNLLHFKTQYSNCPTCGANNTDEV
IEASLPYLLLFAT---DGPATVDC--DEDAVGTVVFVGSTNS--GHC--YTQAAGQ--AF
DNLAKDRKFGKKSPYITAMY--------------------TRFAFKNETSLPVAKQSKGK
SKSVKEDVS--NLATSSKASFDNLTD---------------------------FEQWYDS
NIYESLKVQESPDNFDKYVSFTTK------------------------------------
----------------------------------------------------------ED
SKLPLTLKVR-----GIKSVVDFRSKDGFIYKLTPDTDENSKAPVYYPVLDAISLKAIWV
EGNANFVVGHPNYYSKSLHIPT--------------FWENAENFVKMGDKIGGVTMGLWR
AEHLNKPNLERIFNIAKKAIVGSSVVTTQCGKLIGKAATFIADKVGGGVVRNITDSIKGL
CGITRGHFERKMSPQFLKTLMFFLFYFLKASVKSVVASYKTVLCKVVLATLLIVWFVYTS
NPVMFTGIRVLD-----------------FLFEGSLCGPYKD-YGKDS-FDVLRYCAD-D
FICRVCLHDKDSLHLYKHAYSVEQVYKDAASGFIFNWNWLYLVFLILFVKPVAGFVIICY
CVKYLVLNSTVLQTGVCFLD--WFVQTVF-----SHFNFMGAGF-YFWLFYKIYIQVHHI
LY-CKDVTCEVCKRVARSNRQEVSVVVGGRKQIVHVYTNSGYNFCKRHNWYCRNCDDYGH
QNTFMSPEVAGELSEKLKRHVKPTAYAYHVVDEACLVDDFVNLKYKAATPGKDSASSAVK
CFSVTDFLKKAVFLKE--ALKCEQISNDGFIVCNTQSAHALEEAKNAAIYYAQYLCKPIL
ILDQALYEQL-VVEPVSKSVIDKVCSILSSIISVDTAALNYK------------------
---AGTLR----DALLSITKDEEAVDMAIFCHNHDVDYTGDGFTNVIPSYGIDTGK-LTP
RDRGFLINADASIANLRV--KNAPPVVWKFSELIKLSDSCLKYLISATVKSGVRFFITKS
GAKQVIACHTQKL--LVEKKAG
>AY646283_IBV-partridge_Partridge/GD/S14/2003_nsp3_2353..7176_4824bp_1608aa
--GKTVTFGET-TVKEIPPPDVVP-IKVSIECCGEPWNTIFKKAYKEPIEVETDLTVEQL
LSVIYEKMCDDLKLF-----PEAPEPPPF--------ENVALVDKNGKDLDCIKSCHLVY
RDYESDDDIEE------------------------------EDAEECDTASDDAEECDTG
S----------------ECEEEDEGTKVLA------------------------------
--------------LIQDPASQKYPLPLDDDYSVYNGCIVHKDALDVVNLPSG-------
---------EETFVINN---------------CFEGAVKQLPKSVVDVLGDWGEAVDAQE
KSLNDVADSSSVSLPIEEPVIIHEQEFVPVVEEELDVIVC---TPAELSVVKEAPGEVDE
FILIPSVSNGEEVVSTVSAPQQEESRE------------------------EVVPDILQQ
EEPKIEEPPQVVKIQRERKAKK-------FKVKPTTQKAPN-------------------
-------------------------------CLEYKTCV--GDLTVVIAKALDEFKEFCL
VNAANDYMFHGGGVAKAIADFCGPDFVEYCEDYVKKHGPQK---RLVTPSYVKGIQ--CV
NNVVGP--RHADIDVFGKLLIAYKNVIVDGVVNYVVPVLSSGIFGVDFKLSIDAMRAAFK
DCNIRVLLFSLNQ-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------DHIDYFDATCK
QK----------------------------------------------------TIYLTE
DGVKYRSGVKYRSVIVKPGDSLSQF--GQVFTRHKTV---FTADDVEDKEILFIPTTD--
--KAVLDYYGLDAKKY---VIYLHTLSQKWKIQCKDNFIQLEWRDGNCWINSAIVILQAA
K-IKFKGF-LAEAWAKLLGGDPTDFVAWCYASCNANVGDFSDTNWLSANLAEYFEVDYTN
ALLK-KRVSCN-C----GVKNYEFRGLEACIQPVKAPNLLHFKTQYSNCLTCGSNSVDEV
IEASLPYLLLLAT---DGPAAVDC--DENAVGNVVFIGSTNS--GHC--YTQAAGK--AF
DNLAQDRKFGKKSPYITAMY--------------------TRFSLKSKNLMPIAKKSKGK
NQVVKEDVS--NLAISSKASFDNLTD---------------------------FEQWYDS
NIYESLKVQETPDNLYEYVSFTTK------------------------------------
----------------------------------------------------------ED
SKLPLTLKVR-----GIKSVVDFKSKDGFTYKLTPDTDENSKAPVYYPVLDSVSLKAIWV
DGSANFVVGHPNYNSRALRIPT--------------FWEYAESFVKMGVKVNGVTMGLWR
AEHLNKPNLENLFNIVKKMIVGTNIITTQCGRLIGKTASFIADKVGDGVVLNVTDRIKGC
FGFTREHFERRVSLQFFKTLFFFFFCLLKASVKSLLSSYKSVLRKVVFTALLILWFVYTS
NPVIFTGIRVLD-----------------FLLEGSFCSPYAD-YGKES-FDILRYCGS-D
FTCRVCLHGKDSLHLYKHAYSVKQFYKDAVNGISFTWNWLYMLFLILFVKPVAGFVIICY
CIRYLVLSTTVLQTGVGFLD--WFVQTVF-----ANFNFMGAGF-YFWLFYKIYIQVHHI
MY-CKDITCEVCKKVARSNRHEVSVVVNGRKQLVHVYTNSGYTFCKKHNWYCKNCDKYGH
QNTFMSPEVAGELSEKLKRHVKPTAHAYHVVDDACLVDDFVNLKYNAATPGKEGVHSAVK
CFSVSDFLKKAVFLKD--AQKCEQIANDSFIVCNTHSAHALEEAKNAAIYYAQCLCKPIL
ILDQALYDQL-IVEPVSKSVVDKVCNILSNIISVDSAALNYK------------------
---AGTLR----DALLSVTKDEEAVDMAIFCHNNDVEYTTDGFTNVVPSYGIDTDK-LTP
RDRGFLINADAAIANLKV--KNSPPVVWKYSDLVKLSDSCLKYLISATVKSGGRFFITRS
GAKQVIACYTQKL--LVEKKAG
>AY641576_IBV-peafowl_Peafowl/GD/KQ6/2003_nsp3_2548..7266_4719bp_1573aa
--GKTVTFGET-TVQEIPPPDVVF-IKVSIECCGEPWNTIFKKAYKEPIEVEKDLTVEQL
LSVVYEKMCDDLKSF-----PEAPEPPPF--------ENVALVDKNGKDLDCIKSCHLIY
RDYESDDDIEE------------------------------EDAEECDTDL---------
-----------------ECEEEDEDTKVLA------------------------------
--------------LIQDPASNKYPLPLDDDYSVFNGCIVHKDALDVVNLPSG-------
---------EETFVVNN---------------CFEGAVKPLPQKVVDVLGDWGEAVDAQ-
-------EQIAQTTSEETPISSLEATIEQVVVEEQKIISV---VEEEQQVAVYTPADLQV
VEETP-----DEFILIADVSTEEIVPH------------------------------EEK
ESQIEQEPIQVVKSQREKKAKK-------FKVKSTTCEKPK-------------------
-------------------------------FLEYTTCV--GDLTVVIAKALDEFKEFCI
VNAANEHMSHGGGVAKAIADFCGPDFVEYCADYVKKHGPQQ---KLVTPSFVKGIQ--CV
NNVVGP--RHGDSNLREKLVAAYKSVLVGGVVNYVVPVLSSGIFGVDFKMSIDAMREASK
GCAIRVLLFSLSQ-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------EHIDYFDATCK
QK----------------------------------------------------TIYLTE
D------GVKYRSVVLKPGDSLGQF--GQVFARNKVV---FSADDVEDKEILFIPTTD--
--KTILEYYGLDAQKY---VIYLQTLAQKWDVQYRDNFVILEWRDGNCWISSAIVLLQAA
K-IRFKGF-LAEAWAKLLGGDPTDFVAWCYASCNAKVGDFSDANWLLANLAEHFDADYTN
ALLK-KCVSCN-C----GVKSYELRGLEACIQPVRAPNLLHFKTQYSNCPTCGASSTDEV
IEASLPYLLLFAT---DGPATVDC--DENAVGTVVFIGSTNS--GHC--YTQADGK--AF
DNLAKDRKFGRKSPYITAMY--------------------TRFSLRSENPLLVVEHSKGK
AKVVKEDVS--NLATSSKASFDDLTD---------------------------FEQWYDS
YIYESLKVQETPDNLDEYVSFTTK------------------------------------
----------------------------------------------------------ED
SKLPLTLKVR-----GIKSVVDFRSKDGFTYKLTPDTDENSKTPVYYPVLDSISLRAIWV
EGSANFVVGHPNYHSKSLRIPT--------------FWENAESFVKMGYKIDGVTMGLWR
AEHLNKPNLERIFNIAKKAIVGSSVVTTQCGKILVKAATYVADKVGDGVVRNITDRIKGL
CGFTRGHFEKKMSLQFLKTLVFFFFYFLKASAKSLVSSYKIVLCKVVFATLLIVWFIYTS
NPVVFTGIRVLD-----------------FLFEGSLCGPYND-YGKDS-FDVLRYCAG-D
FTCRVCLHDRDSLHLFKHAYSVEQIYKDAASGINFNWNWLYLVFLILFVKPVAGFVIICY
CVKYLVLSSTVLQTGVGFLD--WFVKTVF-----THFNFMGAGF-YFWLFYKIYVQVHHI
LY-CKDVTCEVCKRVARSNRQEVSVVVGGRKQIVHVYTNSGYNFCKRHNWYCRNCDDYGH
QNTFMSPEVAGGLSEKLKRHVKPTAYAYHVVYEACVVDDFVNLKYKAAIPGKDNASSAVK
CFSVTDFLKKAVFLKE--ALKCEQISNDGFIVCNTQSAHALEEAKNAAIYYAQYLCKPIL
ILDQALYEQL-IVEPVSKSVIDKVCSILSNIISVDTAALNYK------------------
---AGTLR----DALLSITKDEEAVDMAIFCHNHEVEYTGDGFTNVIPSYGMDTGK-LTP
RDRGFLINADASIANLRV--KNAPPVVWKFSDLIKLSDSCLKYLISATVKSGGRFFITKS
GAKQVISCHTQKL--LVEKKAG