Target desc: NC_004718_SARS-human_Tor2_nsp3_2719..8484_5766bp_1922aa JCMM | JCSG
Godzik Lab
BIMR
Crystallization class:  5 




Crystallization classes Help
1 Optimal
2 Suboptimal
3 Average
4 Difficult
5 Very difficult







Homologs (by PSI-BLAST)
Non-redundant NR database (NR60) 163
Solved strucutres (PDB) 14
 Comparison of target features with distributions of crystallization probabilities obtained from TargetDB Help
Protein features
Length1922
Molecular weight 213806
Gravy index-0.15
Isoelectic point5.35
Instability index37.54
Predictions
Transmembrane helices (number)3
Signal peptides (length)No
Longest disorder reg.32
Longest low complexity reg. 34
Coiled coils21
% disorder residues 4
% coil residues36
% helix residues 33
% strand residues 31
Other
Number of Cys residues 52
Number of Met residues 46
Number of Trp residues 18
Number of Tyr residues 83
Number of Phe residues 79
Epsilon 280 222670
Insertions score0.10
 1...*...10....*...20....*...30....*...40....*...50....*...60....*...70....*...80....*...90....*..100
APIKGVTFGEDTVWEVQGYKNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDEWSVATFYLFDDAGEENFS

....*..110....*..120....*..130....*..140....*..150....*..160....*..170....*..180....*..190....*..200
SRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAI

....*..210....*..220....*..230....*..240....*..250....*..260....*..270....*..280....*..290....*..300
KCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNS

....*..310....*..320....*..330....*..340....*..350....*..360....*..370....*..380....*..390....*..400
QDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTT

....*..410....*..420....*..430....*..440....*..450....*..460....*..470....*..480....*..490....*..500
LEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEA

....*..510....*..520....*..530....*..540....*..550....*..560....*..570....*..580....*..590....*..600
KTALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLN

....*..610....*..620....*..630....*..640....*..650....*..660....*..670....*..680....*..690....*..700
EPLVTMPIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTLESP

....*..710....*..720....*..730....*..740....*..750....*..760....*..770....*..780....*..790....*..800
VEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDES

....*..810....*..820....*..830....*..840....*..850....*..860....*..870....*..880....*..890....*..900
FLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANL

....*..910....*..920....*..930....*..940....*..950....*..960....*..970....*..980....*..990....*.1000
ESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITA

....*.1010....*.1020....*.1030....*.1040....*.1050....*.1060....*.1070....*.1080....*.1090....*.1100
KETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDL

....*.1110....*.1120....*.1130....*.1140....*.1150....*.1160....*.1170....*.1180....*.1190....*.1200
NQMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLAC

....*.1210....*.1220....*.1230....*.1240....*.1250....*.1260....*.1270....*.1280....*.1290....*.1300
ESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAY

....*.1310....*.1320....*.1330....*.1340....*.1350....*.1360....*.1370....*.1380....*.1390....*.1400
VKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLG

....*.1410....*.1420....*.1430....*.1440....*.1450....*.1460....*.1470....*.1480....*.1490....*.1500
SLICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLL

....*.1510....*.1520....*.1530....*.1540....*.1550....*.1560....*.1570....*.1580....*.1590....*.1600
GLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGG

....*.1610....*.1620....*.1630....*.1640....*.1650....*.1660....*.1670....*.1680....*.1690....*.1700
RGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVI

....*.1710....*.1720....*.1730....*.1740....*.1750....*.1760....*.1770....*.1780....*.1790....*.1800
VFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGV

....*.1810....*.1820....*.1830....*.1840....*.1850....*.1860....*.1870....*.1880....*.1890....*.1900
VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFR

....*.1910....*.1920..
LTCATTRQVVNVITTKISLKGG

Legend
LOOP loop secondary structure predicted by PSIPRED Download a file
HELIX helix secondary structure predicted by PSIPRED
STRAND strand secondary structure predicted by PSIPRED
DISORDER disordered region predicted by DISOPRED2 Download a file
LOW COMPLEXITY low complexity region predicted by SEG Download a file
COILS coiled coils region predicted by COILS Download a file
TRANSMEMBRANE HELICES transmembrane helices predicted by TMHMM Download a file
SIGNAL PEPTIDES signal peptites predicted by RPSP


Download
FASTA sequencetext file with protein sequence in FASTA format Download a file
Summarytext file with a summary of protein featuresDownload a file

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This server is supported by the NIH Protein Structure Initiative grants: P20 GM076221 (JCMM) and U54 GM074898 (JCSG).

Last update August 30, 2007